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对机构老年人中流感样疾病暴发的监测。

Surveillance for outbreaks of influenza-like illness in the institutionalized elderly.

机构信息

National Centre for Immunisation Research and Surveillance for Vaccine Preventable Diseases, The Children's Hospital at Westmead, University of Sydney, NSW 2052, Australia.

出版信息

Epidemiol Infect. 2010 Aug;138(8):1126-34. doi: 10.1017/S0950268809991440. Epub 2009 Dec 17.

Abstract

Respiratory outbreaks are common in aged-care facilities (ACFs), are both underreported and frequently identified late, and are often associated with considerable burden of illness and death. There is emerging evidence that active surveillance coupled with early and systematic intervention can reduce this burden. Active surveillance for influenza-like illness and rapid diagnosis of influenza were established in 16 ACFs in Sydney, Australia, prior to the winter of 2006. A point-of-care influenza test and laboratory direct immunofluorescence tests for common respiratory viruses were used for diagnosis. We achieved early identification of seven respiratory disease outbreaks, two of which were caused by influenza. For the influenza outbreaks, antiviral treatment and prophylaxis were initiated 4-6 days from symptom onset in the primary case. A simple active surveillance system for influenza was successfully implemented and resulted in early detection of influenza and other respiratory disease outbreaks. This enabled earlier implementation of prevention and control measures and increased the potential effectiveness of anti-influenza chemoprophylaxis.

摘要

呼吸道疾病爆发在养老院中很常见,不仅漏报情况严重,而且往往发现较晚,还常常导致严重的疾病负担和死亡。现有证据表明,积极监测并结合早期和系统的干预措施可以减轻这一负担。在澳大利亚悉尼的 16 家养老院中,在 2006 年冬季之前,已经建立了针对流感样疾病的主动监测和快速流感诊断。使用即时护理流感检测和常见呼吸道病毒的实验室直接免疫荧光检测进行诊断。我们成功地早期识别了七起呼吸道疾病爆发事件,其中两起是由流感引起的。对于流感爆发,在原发性病例出现症状后的 4-6 天开始进行抗病毒治疗和预防。我们成功实施了一个简单的流感主动监测系统,实现了对流感和其他呼吸道疾病爆发的早期检测。这使得更早地实施预防和控制措施成为可能,并提高了抗流感化学预防的潜在效果。

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