Department of Community Health Sciences, University of Manitoba.Winnipeg Regional Health Authority.Department of Medical Microbiology, University of Manitoba, Winnipeg, Canada.
Influenza Other Respir Viruses. 2013 Nov;7(6):1055-61. doi: 10.1111/irv.12052. Epub 2012 Nov 12.
Outbreaks of influenza-like illness (ILI) are common in long-term care facilities (LTCFs) and result in significant morbidity and mortality among residents.
We describe patterns of reported ILI outbreaks in LTCFs in Winnipeg, Canada, and examine LTCF and outbreak characteristics that influence the clinical outcomes of these outbreaks.
We analyzed the electronic records of all ILI outbreaks reported by LTCFs in Winnipeg from 2003 to 2011. Outbreak duration, ILI attack rates among staff and residents, and residents' death rates were calculated by presumed viral etiology, staff vaccination rates, type of influenza chemoprophylaxis used, and time to notification to public health.
Of a total of 154 reported outbreaks, most (N=80) were attributed to influenza, and these outbreaks tended to have higher attack and death rates among LTCF residents compared with outbreaks caused by other respiratory viruses (12) or those of unknown etiology (62). About 92% of residents and 38% of staff of the average LTCFs were vaccinated. Chemoprophylaxis was used in 57·5% of influenza outbreaks. Regardless of presumed viral etiology, outbreaks reported within 3 days of onset ended sooner and had lower attack and mortality rates among residents.
Influenza-like illness outbreaks still occur among highly immunized LTCF residents, so in addition to vaccination of staff and residents, it is important to maintain competent infection control practices. Early identification and notification to public health authorities and possibly early initiation of control measures could improve clinical outcomes of ILI outbreaks.
流感样疾病(ILI)在长期护理机构(LTCF)中很常见,导致居民发病率和死亡率显著增加。
我们描述了加拿大温尼伯市 LTCF 中报告的 ILI 暴发模式,并研究了影响这些暴发临床结果的 LTCF 和暴发特征。
我们分析了 2003 年至 2011 年温尼伯市所有 LTCF 报告的 ILI 暴发的电子记录。根据假定的病毒病因、员工疫苗接种率、使用的流感化学预防类型以及向公共卫生部门报告的时间,计算暴发持续时间、员工和居民的 ILI 发病率以及居民死亡率。
在总共报告的 154 次暴发中,大多数(N=80)归因于流感,与其他呼吸道病毒(12)或病因不明的暴发(62)相比,这些暴发在 LTCF 居民中的发病率和死亡率更高。平均 LTCF 的大约 92%的居民和 38%的员工接受了疫苗接种。化学预防措施在 57.5%的流感暴发中使用。无论假定的病毒病因如何,报告发病后 3 天内的暴发结束得更早,居民的发病率和死亡率更低。
尽管高度免疫的 LTCF 居民仍会发生流感样疾病暴发,因此除了员工和居民的疫苗接种外,保持有效的感染控制措施也很重要。及早发现并向公共卫生当局报告,并可能及早采取控制措施,可能会改善 ILI 暴发的临床结果。