Department of Oral and Maxillofacial Surgery/Oral Pathology, VU University Medical Center/Academic Centre for Dentistry Amsterdam (ACTA), The Netherlands.
Int J Oral Maxillofac Surg. 2010 Mar;39(3):256-9. doi: 10.1016/j.ijom.2009.10.024. Epub 2009 Dec 16.
This study retrospectively investigates the incidence and risk factors for venous thromboembolism (VTE) in patients undergoing maxillofacial surgery. Data were obtained from patients treated between January 2005 and June 2006. Patients' records were reviewed for complaints and information relating to deep venous thrombosis (DVT) and pulmonary embolism (PE). All patients completed a questionnaire on complaints relating to DVT and PE. The patients were classified according to risk and the incidence of reported DVT and PE was calculated. The study population comprised 411 patients with a mean age of 32 (+/- 17) years. The median postoperative follow-up period was 53 (23-639) days. None of the patients received thromboembolism prophylaxis. The incidence of VTE in the study group was 0.5%. Logistic regression analysis demonstrated a relationship between body mass index and hospital stay with thromboembolism (p<0.05). Patients undergoing pre-implant surgery with bone graft proved to be at risk (p=0.07). The incidence of VTE in oral and maxillofacial surgery seems to be low, but thromboembolism prophylaxis may be justified in patients with clear potential risk factors.
本研究回顾性调查了行颌面外科手术患者静脉血栓栓塞症（VTE）的发生率和危险因素。数据来自于 2005 年 1 月至 2006 年 6 月期间治疗的患者。回顾患者的病历以获取有关深静脉血栓形成（DVT）和肺栓塞（PE）的投诉和信息。所有患者均完成了一份有关 DVT 和 PE 投诉的问卷。根据风险对患者进行分类，并计算报告的 DVT 和 PE 的发生率。研究人群包括 411 名平均年龄为 32（+/-17）岁的患者。术后中位随访时间为 53（23-639）天。没有患者接受血栓栓塞预防治疗。研究组 VTE 的发生率为 0.5%。Logistic 回归分析显示，体重指数和住院时间与血栓栓塞之间存在关系（p<0.05）。接受植骨术前手术的患者存在风险（p=0.07）。口腔颌面外科手术中 VTE 的发生率似乎较低，但对于有明确潜在危险因素的患者，可能有必要进行血栓栓塞预防治疗。
