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围手术期的无创呼吸支持。

Noninvasive respiratory support in the perioperative period.

机构信息

Department of Environmental Medicine, Health and Safety, University of Insubria, Varese, Italy.

出版信息

Curr Opin Anaesthesiol. 2010 Apr;23(2):233-8. doi: 10.1097/ACO.0b013e328335daec.

Abstract

PURPOSE OF REVIEW

The aims of this review are: to discuss the physiological rationale for noninvasive respiratory support (NRS) in the perioperative period; to give some practical recommendations to safely apply NRS; and to review available clinical data on preventive and curative NRS after cardiac, thoracic and abdominal surgery.

RECENT FINDINGS

The most important morbid postoperative pulmonary complication is atelectasis formation, which increases significantly the risk for pneumonia and hypoxic acute respiratory failure. NRS refers to techniques allowing respiratory support without the need for an invasive airway. Two types of NRS are commonly used: noninvasive continuous positive airway pressure (nCPAP) and noninvasive positive pressure ventilation (nPPV). NRS may be an important tool to prevent (prophylactic treatment) or to treat acute respiratory failure avoiding intubation (curative treatment). The aims of NRS are: to partially compensate for the affected respiratory function by reducing the work of breathing; to improve alveolar recruitment with better gas exchange (oxygenation and ventilation); to reduce left ventricular afterload, increasing cardiac output and improving hemodynamics. Evidence suggests that NRS has been proven to be an effective strategy to reduce intubation rates, nosocomial infections, ICU and hospital lengths of stay, morbidity and mortality in postoperative patients. However, before initiating NRS any surgical complications must be treated.

SUMMARY

The application of postoperative NRS by a trained and experienced ICU team, with careful patient selection, should optimize patient outcome.

摘要

目的综述

本次综述的目的是:讨论围手术期无创呼吸支持(NRS)的生理原理;提出一些安全应用 NRS 的实用建议;并回顾心脏、胸部和腹部手术后预防性和治疗性 NRS 的现有临床数据。

最近的发现

术后最重要的肺部并发症是肺不张形成,这大大增加了肺炎和低氧性急性呼吸衰竭的风险。NRS 是指无需侵入性气道即可进行呼吸支持的技术。两种类型的 NRS 通常被使用:无创持续气道正压通气(nCPAP)和无创正压通气(nPPV)。NRS 可能是预防(预防性治疗)或治疗急性呼吸衰竭(治疗性治疗)而避免插管的重要工具。NRS 的目的是:通过减少呼吸功来部分补偿受影响的呼吸功能;通过更好的气体交换(氧合和通气)来改善肺泡募集;减少左心室后负荷,增加心输出量并改善血流动力学。有证据表明,NRS 已被证明是降低术后患者插管率、医院感染率、重症监护病房和医院住院时间、发病率和死亡率的有效策略。然而,在开始 NRS 之前,必须治疗任何手术并发症。

总结

由经过培训和经验丰富的 ICU 团队应用术后 NRS,并进行仔细的患者选择,应能优化患者的预后。

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