Lattouf Jean-Baptiste
Department of Surgery, Urologic Oncology Section and Minimally Invasive Section, University of Montréal Health Centre (CHUM), Montréal, QC.
Can Urol Assoc J. 2009 Dec;3(6 Suppl 4):S184-7. doi: 10.5489/cuaj.1193.
Bladder cancer is the sixth most common tumour in Canada and ranks eighth in terms of cancer mortality. Up to now, management of this condition relied mostly on surgical and intravesical treatments once the disease is established. Chemoprevention is an attractive option to prevent the disease in high-risk populations and may well reduce the costs related to its treatment. This review examines the available data on chemoprevention strategies in bladder cancer, with special emphasis on randomized controlled trials when available.
膀胱癌是加拿大第六大常见肿瘤,在癌症死亡率方面排名第八。到目前为止,一旦疾病确诊,这种疾病的治疗主要依靠手术和膀胱内治疗。化学预防是预防高危人群患膀胱癌的一种有吸引力的选择,并且很可能降低其治疗相关成本。本综述研究了膀胱癌化学预防策略的现有数据,特别强调了现有随机对照试验。