Department of Radiology, Driscoll Children's Hospital, 3533 S. Alameda St., Corpus Christi, TX 78411, USA.
Pediatr Radiol. 2010 Feb;40(2):200-5. doi: 10.1007/s00247-009-1487-z. Epub 2009 Dec 18.
Since the World Health Organization declared a global pandemic of novel influenza A H1N1 in June 2009, there has been a sustained rise in the number of cases of this strain of influenza. Although most cases are mild with complete and uneventful recovery, multiple cases of severe infection with complications including death have been reported. To the best of our knowledge, the majority of fatal outcomes in the United States have been related to pulmonary complications. We report a 12-year-old girl infected with influenza A H1N1 whose clinical course was complicated by rapid progressive neurologic deterioration and striking CT and MRI findings consistent with acute necrotizing encephalopathy (ANE). To our knowledge this has not been reported in the pediatric radiology literature. We hope this case will alert radiologists to this complication and familiarize radiologists with imaging findings that herald ANE.
自 2009 年 6 月世界卫生组织宣布新型甲型 H1N1 流感大流行以来，该流感株的病例数持续上升。虽然大多数病例症状轻微，完全恢复，没有出现并发症，但也有许多严重感染的病例，包括死亡。据我们所知，美国大多数致命病例与肺部并发症有关。我们报告了一例感染甲型 H1N1 的 12 岁女孩，其临床病程复杂，表现为快速进展性神经功能恶化，以及与急性坏死性脑病（ANE）一致的显著 CT 和 MRI 表现。据我们所知，儿科放射学文献中尚未报道过这种情况。我们希望本病例能引起放射科医生的注意，并使放射科医生熟悉预示 ANE 的影像学表现。
