University of Louisville, Louisville, KY, USA.
Arch Womens Ment Health. 2010 Aug;13(4):307-17. doi: 10.1007/s00737-009-0125-y. Epub 2009 Dec 18.
This phase 1 clinical trial combined qualitative and quantitative methods to modify a collaborative care, telephone-based, depression care management intervention for adolescent mothers and to determine the acceptability, feasibility, and initial efficacy of the intervention in a sample of adolescent mothers (n = 97) who were recruited from a Teen Parent Program. Outcomes included measures of depressive symptoms, functioning, and use of mental health services. Acceptability of the intervention was demonstrated, but feasibility issues related to the complex life challenges confronting the adolescent mother. Although only four adolescent mothers received mental health treatment, there was a trend for improved depressive symptoms over time. Results of the study provide data for the need of further refinement of the intervention before a large clinical trial is conducted for adolescent mothers with symptoms of depression.
这项 1 期临床试验采用定性和定量方法相结合,对基于电话的合作式护理、青少年母亲抑郁管理干预措施进行了修改,并在从青少年父母项目中招募的 97 名青少年母亲样本中,对该干预措施的可接受性、可行性和初步效果进行了评估。结果指标包括抑郁症状、功能和精神卫生服务的使用情况。该干预措施具有可接受性,但与青少年母亲面临的复杂生活挑战相关的可行性问题。尽管只有 4 名青少年母亲接受了心理健康治疗,但抑郁症状随时间推移呈现改善趋势。该研究结果为进一步完善针对有抑郁症状的青少年母亲的干预措施提供了数据,以便在进行大型临床试验之前。