Warwick Medical School, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL, UK.
Trials. 2011 Mar 25;12:88. doi: 10.1186/1745-6215-12-88.
Postnatal depression (PND) can be experienced by 13% of women who give birth, and such women often exhibit disabling symptoms, which can have a negative effect on the mother and infant relationship, with significant consequences in terms of the child's later capacity for affect regulation. Research has shown that providing support to mothers experiencing PND can help reduce their depressive symptoms and improve their coping strategies. The Mums4Mums study aims to evaluate the impact of telephone peer-support for women experiencing PND.
METHODS/DESIGN: The study design adopts the MRC framework for the development and evaluation of complex interventions. Health visitors in Warwickshire and Coventry Primary Care Trusts are screening potential participants at the 8-week postnatal check using either the Edinburgh Postnatal Depression Scale (EPDS > = 10) or the three Whooley questions recommended by NICE (http://guidance.nice.org.uk/CG45). The Mums4Mums telephone support intervention is being delivered by trained peer-supporters over a period of four months. The primary outcome is depressive symptomatology as measured by the Edinburgh Postnatal Depression Scale. Secondary outcomes include mother-child interaction, dyadic adjustment, parenting sense of competence scale, and self-efficacy. Maternal perceptions of the telephone peer-support are being assessed using semi-structured interviews following the completion of the intervention.
The proposed study will develop current innovative work in peer-led support interventions and telecare by applying existing expertise to a new domain (i.e. PND), testing the feasibility of a peer-led telephone intervention for mothers living with PND, and developing the relationship between the lay and clinical communities. The intervention will potentially benefit a significant number of patients and support a future application for a larger study to undertake a full evaluation of the clinical and cost effectiveness of telephone based peer-support for PND.
ISRCTN: ISRCTN91450073. The study has received a major funding grant from National Institute for Health Research (NIHR) (UK) - Research for Patient Benefit (RfPB) programme (ref: PB-PG-0407-13232).
产后抑郁症（PND）可影响 13%的产妇，此类女性常出现致残症状，这可能对母婴关系产生负面影响，并对儿童日后的情绪调节能力产生重大影响。研究表明，为患有 PND 的母亲提供支持有助于减轻其抑郁症状并改善其应对策略。Mums4Mums 研究旨在评估针对患有 PND 的女性提供电话同伴支持的效果。
方法/设计：研究设计采用 MRC 框架来开发和评估复杂干预措施。沃里克郡和考文垂初级保健信托的健康访视员正在 8 周产后检查时使用爱丁堡产后抑郁量表（EPDS≥10）或 NICE 推荐的三个 Whooley 问题（http://guidance.nice.org.uk/CG45）筛查潜在参与者。Mums4Mums 电话支持干预由经过培训的同伴支持者在四个月内提供。主要结局是使用爱丁堡产后抑郁量表测量的抑郁症状。次要结局包括母婴互动、夫妻适应、育儿胜任感量表和自我效能感。在干预完成后，通过半结构化访谈评估母亲对电话同伴支持的看法。
拟议的研究将通过将现有专业知识应用于新领域（即 PND）来扩展当前关于同伴主导支持干预和远程护理的创新工作，测试针对患有 PND 的母亲的同伴主导电话干预的可行性，并发展准专业人士和临床社区之间的关系。该干预措施可能使大量患者受益，并支持未来申请更大规模的研究，以对 PND 的基于电话的同伴支持的临床和成本效益进行全面评估。
ISRCTN：ISRCTN91450073。该研究得到了英国国家卫生研究院（NIHR）（英国） - 患者受益研究（RfPB）计划（参考：PB-PG-0407-13232）的重大资助。
