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快速通讯:彗星试验检测止汗剂诱发犬细胞 DNA 损伤。

Rapid communications: antiperspirant induced DNA damage in canine cells by comet assay.

机构信息

Pomona College, Claremont, California, USA.

出版信息

Toxicol Mech Methods. 2004;15(1):25-8. doi: 10.1080/15376520590890677.

DOI:10.1080/15376520590890677
PMID:20021076
Abstract

Abstract Millions of people around the world use antiperspirants to decrease or eliminate body odors. Most antiperspirants contain aluminum zirconium or another form of aluminum as its active ingredient. The present investigation applied Comet assay to detect if Secret Platinum for women, Old Spice for men, or Crystal Natural produced DNA damage in Madin-Darby canine kidney cells (MDCKII). This study has shown that antiperspirants cause DNA damage on a single-cell level. Additionally, our data showed us that in general, Secret Platinum for women and Old Spice for men, produced equivalent damage. Crystal Natural, marketed as being safer or less damaging, induced the most extensive damage of all three antiperspirants tested.

摘要

摘要

全球数百万人使用止汗剂来减少或消除体臭。大多数止汗剂都含有铝锆或其他形式的铝作为其有效成分。本研究应用彗星试验检测 Secret Platinum for women、Old Spice for men 或 Crystal Natural 是否会在 Madin-Darby 犬肾细胞(MDCKII)中造成 DNA 损伤。本研究表明,止汗剂会在单细胞水平上造成 DNA 损伤。此外,我们的数据还表明,一般来说,Secret Platinum for women 和 Old Spice for men 产生的损伤相当。而被宣传为更安全或损伤更小的 Crystal Natural 导致了所有三种测试的止汗剂中最广泛的损伤。

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