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昂贵的癌症药物:美国和英国的比较。

Expensive cancer drugs: a comparison between the United States and the United Kingdom.

机构信息

Johns Hopkins University, Baltimore, MD 21205, USA.

出版信息

Milbank Q. 2009 Dec;87(4):789-819. doi: 10.1111/j.1468-0009.2009.00579.x.

DOI:10.1111/j.1468-0009.2009.00579.x
PMID:20021586
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2888017/
Abstract

CONTEXT

This article compares the United Kingdom's and the United States' experiences with expensive cancer drugs to illustrate the challenges posed by new, extremely costly, medical technologies.

METHODS

This article describes British and American coverage, access, and cost-sharing policies with regard to expensive cancer drugs and then compares the costs of eleven such drugs to British patients, American Medicare beneficiaries, and American patients purchasing the drugs in the retail market. Three questions posed by these comparisons are then examined: First, which system is fairer? In which system are cancer patients better off? Assuming that no system can sustainably provide to everyone at least some expensive cancer drugs for some clinical indications, what challenges does each system face in making these difficult determinations?

FINDINGS

In both the British and American health care systems, not all patients who might benefit from or desire access to expensive cancer drugs have access to them. The popular characterization of the United States, where all cancer drugs are available for all to access as and when needed, and that of the British NHS, where top-down population rationing poses insurmountable obstacles to British patients' access, are far from the reality in both countries.

CONCLUSIONS

Key elements of the British system are fairer than the American system, and the British system is better structured to deal with difficult decisions about expensive end-of-life cancer drugs. Both systems face common ethical, financial, organizational, and priority-setting challenges in making these decisions.

摘要

背景

本文比较了英国和美国在昂贵癌症药物方面的经验,以说明新的、极其昂贵的医疗技术所带来的挑战。

方法

本文描述了英国和美国在昂贵癌症药物的覆盖范围、准入和成本分担政策方面的情况,然后比较了 11 种此类药物对英国患者、美国医疗保险受益人以及在美国零售市场购买这些药物的美国患者的成本。然后,考察了这些比较提出的三个问题:首先,哪个系统更公平?在哪个系统中癌症患者的状况更好?假设没有一个系统能够可持续地为至少一些具有某些临床指征的癌症患者提供所有昂贵的癌症药物,那么每个系统在做出这些艰难的决定时都面临哪些挑战?

发现

在英国和美国的医疗保健系统中,并非所有可能受益于或希望获得昂贵癌症药物的患者都能获得这些药物。关于美国的普遍描述是,所有癌症药物都可供所有人在需要时随时获得,而关于英国国民保健制度的描述则是,自上而下的人口配给给英国患者的准入造成了无法克服的障碍,这两种说法都与两国的实际情况相去甚远。

结论

英国制度的关键要素比美国制度更公平,英国制度在处理昂贵的临终癌症药物的艰难决策方面结构更好。在做出这些决策时,两个系统都面临着共同的伦理、财务、组织和优先事项设定方面的挑战。

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