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超声引导下外周神经刺激(PNS)系统永久植入治疗四肢神经病理性疼痛:原始病例和结果。

Ultrasound-guided permanent implantation of peripheral nerve stimulation (PNS) system for neuropathic pain of the extremities: original cases and outcomes.

机构信息

Division of Pain Medicine, Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota, USA.

出版信息

Pain Med. 2009 Nov;10(8):1369-77. doi: 10.1111/j.1526-4637.2009.00745.x.

Abstract

OBJECTIVE

Our objective is to describe our experience applying a minimally invasive, ultrasound-assisted technique for peripheral nerve stimulation (PNS) trial and permanent implantation in patients with neuropathic extremity pain.

DESIGN

Retrospective case series and review of the literature. Setting. Tertiary referral center and academic medical center.

PATIENTS

Patients with upper or lower extremity neuropathic pain resistant to other therapies who responded to an ultrasound-guided peripheral nerve block at a proximal location. Interventions. Ultrasound-assisted through-the-needle placement of percutaneous neurostimulation electrodes on target major peripheral nerves for fully percutaneous trial, staged trial or permanent implantation of PNS system. A PNS trial period of 3-7 days was used.

OUTCOME MEASURES

Pain relief at last follow-up, complications, therapeutic limitations due to technique as applied. Results. Six of eight (75%) patients and 7/9 (78%) peripheral nerves had a successful trial and underwent permanent PNS system implantation using a minimally invasive, ultrasound-assisted technique from November 2007 to December 2008. All but one patient with an implanted PNS system had > or =50% pain relief at last follow-up and 3/7 (43%) permanent systems were associated with > or =80% relief. Loss of paresthesia required revision to dual-lead systems in upper extremity radial nerve PNS. Infection led to explant in one case.

CONCLUSIONS

In a small series of patients, a minimally invasive, ultrasound-assisted technique for PNS trial, and permanent PNS implantation proved feasible. Patients without adequate analgesia during neurostimulation trial avoided surgical incision and those undergoing permanent implantation were not subjected to the potential morbidity associated with nerve dissection.

摘要

目的

我们旨在描述应用微创超声辅助技术进行周围神经刺激(PNS)试验和永久性植入术治疗周围神经病变性肢体疼痛的经验。

设计

回顾性病例系列研究和文献复习。

设置

三级转诊中心和学术医疗中心。

患者

对近端位置的超声引导下周围神经阻滞有反应但对其他治疗方法仍有抵抗的上肢或下肢周围神经病性疼痛患者。

干预措施

在超声引导下将经皮神经刺激电极经皮穿过针,放置在目标主要周围神经上,进行完全经皮试验、分期试验或永久性 PNS 系统植入。使用 3-7 天的 PNS 试验期。

结果测量

最后随访时的疼痛缓解程度、并发症、因技术应用而产生的治疗限制。

结果

2007 年 11 月至 2008 年 12 月,8 例患者中的 6 例(75%)和 9 条外周神经中的 7 条(78%)成功进行了试验,并使用微创超声辅助技术进行了永久性 PNS 系统植入。除了一名植入 PNS 系统的患者外,所有患者在最后一次随访时的疼痛缓解程度均>或=50%,且 3/7(43%)的永久性系统缓解程度>或=80%。上肢桡神经 PNS 中,由于失去感觉而需要对双导联系统进行修正。感染导致 1 例患者的 PNS 系统被取出。

结论

在一项小型患者系列研究中,微创超声辅助技术用于 PNS 试验和永久性 PNS 植入术是可行的。在神经刺激试验期间没有足够镇痛的患者避免了手术切口,而进行永久性植入的患者则不会受到神经解剖相关潜在发病率的影响。

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