[双对比增强超声在胃癌术前分期中的诊断价值]

[Diagnostic value of double contrast-enhanced ultrasonography in preoperative staging of gastric cancer].

作者信息

Wang Cheng-long, Yang Yong-ming, Cui Jian, Ouyang Hong, Wang Zhe-min, Ye Huai-song, Ruan Hua-juan, Zheng Zhi-qiang

机构信息

Department of General Surgery, Lin'an People's Hospital, Lin'an, Zhejiang, China.

出版信息

Zhonghua Zhong Liu Za Zhi. 2009 Sep;31(9):701-4.

PMID:20021869

Abstract

OBJECTIVE

To evaluate the clinical value of double contrast-enhanced ultrasonography using oral and intravenous contrast agents in preoperative staging of gastric cancer.

METHODS

Sixty-two patients with biopsy-proven gastric cancer were enrolled into this study, and were examined by double contrast-enhanced gastric ultrasonography preoperatively. The results were compared with postoperative pathologic findings.

RESULTS

The accuracy of oral contrast-enhanced gastric ultrasonography and double contrast-enhanced ultrasonography in determining the T stage of gastric cancer was 72.9% (T1: 66.7%, T2: 60.0%, T3: 76.9%, T4: 71.4%) and 88.1% (T1: 66.7%, T2: 80.0%, T3: 89.7%, T4: 100%), respectively, with a statistically significant difference between the two methods (P = 0.036). The sensitivity, specificity, accuracy and Youden index of oral contrast-enhanced gastric ultrasonography and double contrast-enhanced ultrasonography in assessment of lymph node metastasis were 74.5%, 66.7%, 72.9%, and 0.41 versus 89.4%, 75.0%, 86.4%, 0.76, respectively. No significant difference in the accuracy of assessment for lymph node metastasis was observed (P > 0.05).

CONCLUSION

Double contrast-enhanced ultrasonography is useful for preoperative staging of gastric cancer, especially for T staging.

摘要

目的

评估口服及静脉造影剂双重对比增强超声检查在胃癌术前分期中的临床价值。

方法

62例经活检证实为胃癌的患者纳入本研究，术前行双重对比增强胃超声检查。将结果与术后病理结果进行比较。

结果

口服对比剂增强胃超声检查和双重对比增强超声检查在确定胃癌T分期方面的准确率分别为72.9%（T1：66.7%，T2：60.0%，T3：76.9%，T4：71.4%）和88.1%（T1：66.7%，T2：80.0%，T3：89.7%，T4：100%），两种方法之间存在统计学显著差异（P = 0.036）。口服对比剂增强胃超声检查和双重对比增强超声检查在评估淋巴结转移方面的敏感性、特异性、准确率和尤登指数分别为74.5%、66.7%、72.9%和0.41，而分别为89.4%、75.0%、86.4%、0.76。在评估淋巴结转移的准确率方面未观察到显著差异（P > 0.05）。