Department of Gastroenterology, Zibo Central Hospital, Zibo, 255000 Shandong, China.
Comput Math Methods Med. 2022 Feb 18;2022:6192190. doi: 10.1155/2022/6192190. eCollection 2022.
This research was aimed at exploring the application value of endoscopic ultrasonography (EUS) in the diagnosis of gastric cancer staging and the correlation between staging and clinical features of gastric cancer. A total of 72 patients with gastric cancer were selected and randomly divided into two groups. The patients in the pathological group underwent postoperative pathological examination, while those in the EUS group received preoperative EUS examination. The results showed that the staging accuracy of EUS was 73.33% for T1, 78.57% for T2, 27% for T3, and 100% for T4, compared with the pathological staging. The accuracy of N- and N+ was 42.5% and 82.3% in EUS, respectively, and the total accuracy was 55.7%. There was no considerable difference in the accuracy of T staging between early gastric cancer and advanced gastric cancer ( > 0.05), but there was a considerable difference in N staging ( < 0.05). Lymph node metastasis affected the accuracy of N staging ( < 0.05). The number and location of metastatic lymph nodes did not affect the judgment of metastatic lymph nodes ( > 0.05). In addition, the proportion of understaging and overstaging was greatly different among different lesion sizes and histological types of gastric cancer ( < 0.05). To sum up, the accuracy of EUS for T and N staging of gastric cancer needed to be improved. The location of gastric cancer lesions affected the accuracy of T staging, while the depth of invasion and lymph node metastasis affected the accuracy of N staging.
本研究旨在探讨内镜超声（EUS）在胃癌分期诊断中的应用价值及与胃癌临床特征的相关性。选取 72 例胃癌患者，随机分为两组，病理组患者术后行病理检查，EUS 组患者术前接受 EUS 检查。结果显示，EUS 对 T1 分期的准确率为 73.33%，对 T2 的准确率为 78.57%，对 T3 的准确率为 27%，对 T4 的准确率为 100%，与病理分期相比。EUS 对 N-和 N+的准确率分别为 42.5%和 82.3%，总准确率为 55.7%。早期胃癌和进展期胃癌 T 分期准确率无显著差异（>0.05），但 N 分期有显著差异（<0.05）。淋巴结转移影响 N 分期的准确性（<0.05）。转移淋巴结的数量和位置不影响对转移淋巴结的判断（>0.05）。此外，不同病变大小和组织学类型的胃癌，其低估和高估的比例有很大差异（<0.05）。综上所述，EUS 对胃癌 T、N 分期的准确率有待提高。胃癌病变部位影响 T 分期的准确性，而浸润深度和淋巴结转移影响 N 分期的准确性。
