Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden.
Urology. 2010 May;75(5):1092-7. doi: 10.1016/j.urology.2009.09.075.
To quantify complications to surgery in patients treated with robot-assisted radical prostatectomy (RARP) and open retropubic radical prostatectomy (RRP) at our institution. Radical prostatectomy is associated with specific complications that can affect outcome results in patients.
Between January 2002 and August 2007, a series of 1738 consecutive patients underwent RARP (n = 1253) or RRP (n = 485) for clinically localized prostate cancer. Surgery-related complications were assessed using a prospective hospital-based complication registry. The baseline characteristics of all patients were documented preoperatively.
Overall, 170 patients required blood transfusions (9.7%), 112 patients (23%) in the RRP group compared with 58 patients (4.8%) in the RARP group. Infectious complications occurred in 44 RRP patients (9%) compared with 18 (1%) in the RARP group. Bladder neck contracture was treated in 22 (4.5%) patients who had undergone RRP compared with 3 (0.2%) in the RARP group. Clavien grade IIIb-V complications were more common in RRP patients (n = 63; 12.9%) than in RARP patients (n = 46; 3.7%).
The introduction of RARP at our institution has resulted in decreased number of patients with Clavien grade IIIb-V complications, such as bladder neck contractures, a decrease in the number of patients who require blood transfusions, and decreased numbers of patients with postoperative wound infections.
量化本机构接受机器人辅助根治性前列腺切除术(RARP)和开放性经耻骨后根治性前列腺切除术(RRP)治疗的患者的手术并发症。根治性前列腺切除术与特定的并发症相关,这些并发症可能会影响患者的治疗结果。
2002 年 1 月至 2007 年 8 月,1738 例连续接受局限性前列腺癌根治性前列腺切除术的患者中,有 1253 例行 RARP,485 例行 RRP。使用前瞻性医院并发症登记处评估与手术相关的并发症。所有患者的术前基线特征均记录在案。
总体而言,170 例患者需要输血(9.7%),RRP 组中有 112 例(23%),而 RARP 组中有 58 例(4.8%)。RRP 组中有 44 例(9%)发生感染性并发症,而 RARP 组中有 18 例(1%)。22 例(4.5%)接受 RARP 的患者出现膀胱颈挛缩,而 RARP 组中有 3 例(0.2%)。RRP 患者的 Clavien Ⅲb-V 级并发症更为常见(n=63;12.9%),而 RARP 患者的 Clavien Ⅲb-V 级并发症较少(n=46;3.7%)。
本机构引入 RARP 后,Clavien Ⅲb-V 级并发症(如膀胱颈挛缩)、需要输血的患者数量以及术后伤口感染的患者数量均有所减少。