Department of Veterinary Clinical Sciences, Faculty of Veterinary Medicine, Università degli Studi di Milano, Milan, Italy.
Theriogenology. 2010 Mar 1;73(4):460-7. doi: 10.1016/j.theriogenology.2009.09.028. Epub 2009 Dec 21.
This experiment was designed to determine the effects of sexual stimulation on plasma concentrations of oxytocin (OT), vasopressin (VP), 15-ketodihydro-PGF(2alpha) (PG-metabolite), luteinizing hormone (LH), testosterone (T), estrone sulfate (ES), and cortisol (C) in stallions. Semen samples were collected from 14 light horse stallions (Equus caballus) of proven fertility using a Missouri model artificial vagina. Blood samples were collected at 15, 12, 9, 6, and 3 min before estrous mare exposure, at erection, at ejaculation, and at 3, 6, and 9 min after ejaculation. Afterwards, blood sampling was performed every 10 min for the following 60 min. Sexual activity determined an increase in plasma concentrations of OT, VP, C, PG-metabolite, and ES and caused no changes in LH and T concentrations. The finding of a negative correlation between C and VP at erection, and between C and T before erection and at the time of erection, could be explained by a possible inhibitory role exerted by C in the mechanism of sexual arousal described for men.
本实验旨在确定性刺激对血浆催产素（OT）、血管加压素（VP）、15-酮二氢-PGF(2alpha)（PG 代谢物）、促黄体生成激素（LH）、睾酮（T）、雌酮硫酸酯（ES）和皮质醇（C）浓度的影响在种马中。使用密苏里模型人工阴道从 14 匹轻型马种马（Equus caballus）中收集精液样本。在发情母马暴露前 15、12、9、6 和 3 分钟、勃起时、射精时以及射精后 3、6 和 9 分钟采集血液样本。之后，在接下来的 60 分钟内每 10 分钟进行一次血液采样。性活动导致 OT、VP、C、PG 代谢物和 ES 的血浆浓度增加，而 LH 和 T 浓度没有变化。在勃起时 C 与 VP 之间以及在勃起前和勃起时 C 与 T 之间存在负相关的发现，可以通过 C 在描述的男性性唤起机制中发挥的可能抑制作用来解释。
