Allergy Clinic, Copenhagen University Hospital, Dept. 7551, Copenhagen, Denmark.
Med Hypotheses. 2010 May;74(5):777-9. doi: 10.1016/j.mehy.2009.11.035. Epub 2009 Dec 21.
Avoidance advices for house-dust mite sensitized persons are currently based upon the idea, that the mites (Dermatophagoides spp.) are part of the indoor fauna. A closer look at development stages in the house-dust samples shows, however, that only the mites' active stages are present there and that the stages between them, the inactive moulting stages, are absent. Therefore the mites probably do not carry out their life cycles in our dwellings, but are more likely contaminations from the open. Findings of low level concentrations can be explained by mites coming from outdoors and sedimented in accordance with known physical laws. The occasional finding of higher concentrations is the result of synchronized populations of the mites developing outdoors and being passively transported into our homes by wind and dust. The hypothesis explains why we find mites in our homes but nonetheless have no effect of avoidance measures. The verification of the entire hypothesis or part of it may have great impact on the management of the disease house-dust mite allergy.
目前，针对屋尘螨致敏人群的回避建议基于这样一种观点，即螨（屋尘螨属）是室内动物群的一部分。然而，仔细观察房屋尘埃样本中的发育阶段可以发现，只有螨的活动阶段存在于其中，而它们之间的阶段，即不活跃的蜕皮阶段，不存在。因此，螨可能不会在我们的住所中完成其生命周期，而更有可能是来自户外的污染。低浓度的发现可以通过螨从户外进入并根据已知的物理定律沉降来解释。偶尔发现较高浓度是螨在户外同步繁殖并被风和灰尘被动带入室内的结果。该假设解释了为什么我们在室内发现螨，但回避措施仍然没有效果。整个假设或其部分的验证可能对屋尘螨过敏症的疾病管理产生重大影响。
