Royal Berkshire Hospital, Reading, RG1 5AN, UK.
Oxford Fertility Unit, Institute of Reproductive Sciences, Oxford Business Park North, Oxford, Oxfordshire, OX4 2HW, UK.
Eur J Obstet Gynecol Reprod Biol. 2010 Mar;149(1):68-71. doi: 10.1016/j.ejogrb.2009.11.017. Epub 2009 Dec 22.
To examine the outcome of IVF in women who have normal ovaries, ovulatory PCO or PCOS.
Analysis of a prospectively collected database in an assisted conception unit in a university teaching hospital including 290 women <37 years of age undergoing their first IVF cycle. The main outcome measure was severe OHSS requiring hospitalization.
Severe OHSS rates were significantly higher in women with PCO (12.6%) and PCOS (15.4%) compared to those with normal ovaries (2.7%). Coasting was used significantly more often. Live birth rates per cycle started are similar among women with PCO (38%), PCOS (37%) and normal ovaries (40%).
Women with ovaries of polycystic morphology are at increased risk of developing severe OHSS and of requiring avoidance techniques such as coasting, regardless of ovulatory status. However, live birth rates per cycle are similar to women with normal ovaries.
研究正常卵巢、排卵多囊卵巢（PCO）或多囊卵巢综合征（PCOS）妇女的体外受精（IVF）结局。
对大学教学医院辅助受孕单位前瞻性收集的数据库进行分析，包括 290 名年龄<37 岁的首次 IVF 周期的妇女。主要观察指标为需要住院治疗的重度卵巢过度刺激综合征（OHSS）。
与正常卵巢（2.7%）相比，PCO（12.6%）和 PCOS（15.4%）妇女重度 OHSS 发生率显著更高。PCO 组和 PCOS 组更常采用 coasting 技术。起始周期活产率在 PCO（38%）、PCOS（37%）和正常卵巢（40%）妇女中相似。
无论排卵状态如何，多囊卵巢形态的卵巢妇女发生重度 OHSS 和需要规避技术（如 coasting）的风险增加。然而，与正常卵巢妇女相比，每个周期的活产率相似。
