Digimagem, 04534-010 São Paulo, Brazil.
Hum Reprod. 2010 Mar;25(3):665-71. doi: 10.1093/humrep/dep433. Epub 2009 Dec 19.
Successful surgical treatment of deep bowel endometriosis depends on obtaining detailed information about the lesions, prior to the procedure. The objective of this study was to determine the capability of transvaginal ultrasonography with bowel preparation (TVUS-BP) to predict the presence of one or more rectosigmoid nodules and the deepest bowel layer affected by the disease.
A prospective study of 194 patients with clinical and TVUS-BP suspected deep endometriosis submitted to videolaparoscopy. Image data were compared with surgical and histological results.
With respect to bowel nodule detection and presence of at least two rectosigmoid lesions, TVUS-BP had a sensitivity of 97 and 81%, specificity 100 and 99%, positive predictive value (PPV) 100 and 93% and negative predictive value (NPV) 98 and 96%, respectively. Regarding diagnosis of infiltration of the submucosal/mucosal layer, TVUS-BP had a sensitivity of 83%, specificity 94%, PPV 77%, NPV 96%.
These findings show that TVUS-BP is an adequate exam for evaluating the presence of one or more rectosigmoid nodules and the deepest layer affected in deep infiltrating bowel endometriosis, confirming the importance of this technique for defining the most appropriate surgical strategy to be implemented.
成功的深部肠子宫内膜异位症手术治疗取决于术前获得关于病变的详细信息。本研究的目的是确定肠道准备经阴道超声(TVUS-BP)预测一个或多个直肠乙状结肠结节以及受疾病影响的最深肠层存在的能力。
对 194 例临床和 TVUS-BP 怀疑深部子宫内膜异位症的患者进行前瞻性研究,并进行腹腔镜检查。将图像数据与手术和组织学结果进行比较。
就肠结节检测和至少存在两个直肠乙状结肠病变而言,TVUS-BP 的灵敏度分别为 97%和 81%,特异性为 100%和 99%,阳性预测值(PPV)分别为 100%和 93%,阴性预测值(NPV)分别为 98%和 96%。对于黏膜下/黏膜层浸润的诊断,TVUS-BP 的灵敏度为 83%,特异性为 94%,PPV 为 77%,NPV 为 96%。
这些发现表明,TVUS-BP 是评估深部浸润性肠子宫内膜异位症中一个或多个直肠乙状结肠结节以及最深层受累的充分检查方法,证实了该技术对于确定要实施的最合适手术策略的重要性。