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肠道准备提高经阴道超声诊断直肠乙状结肠深部浸润型子宫内膜异位症的准确性:一项前瞻性研究。

Bowel Preparation Improves the Accuracy of Transvaginal Ultrasound in the Diagnosis of Rectosigmoid Deep Infiltrating Endometriosis: A Prospective Study.

作者信息

Ros Cristina, Martínez-Serrano María José, Rius Mariona, Abrao Mauricio Simoes, Munrós Jordina, Martínez-Zamora Ma Ángeles, Gracia Meritxell, Carmona Francisco

机构信息

Endometriosis Unit, Institut Clínic de Ginecologia, Obstetrícia i Neonatologia, Hospital Clínic de Barcelona, Universitat de Barcelona, Barcelona, Spain.

Endometriosis Unit, Institut Clínic de Ginecologia, Obstetrícia i Neonatologia, Hospital Clínic de Barcelona, Universitat de Barcelona, Barcelona, Spain.

出版信息

J Minim Invasive Gynecol. 2017 Nov-Dec;24(7):1145-1151. doi: 10.1016/j.jmig.2017.06.024. Epub 2017 Jun 30.

Abstract

STUDY OBJECTIVE

To compare the accuracy of transvaginal ultrasound (TVUS) with and without bowel preparation (BP) to detect and describe intestinal nodules of deep infiltrating endometriosis (DIE) with laparoscopic findings.

DESIGN

A prospective study of paired data (Canadian Task Force classification II.1).

SETTING

A tertiary university hospital from November 2014 to November 2015.

PATIENTS

A cohort of women awaiting surgery for endometriosis.

INTERVENTIONS

The wall of the rectum and the lower sigmoid colon of the patients were evaluated by 2 TVUSs: the first ultrasound was performed without previous BP, and the second was done after a 3-day low-residue diet and two 250-mL enemas 12 hours and 3 hours before TVUS.

MEASUREMENTS AND MAIN RESULTS

The presence or absence of rectosigmoid nodules visualized by TVUS with and without BP was compared with laparoscopic results. Forty patients with a mean age of 36.8 ± 5.0 years were included in the study. By comparing the surgical findings histologically confirmed (the presence or absence of bowel nodules and localization) with those of the 2 TVUSs with and without BP, the sensitivity, specificity, and Cohen kappa were 100%, 96%, and 0.95 and 73%, 88%, and 0.61, respectively. Laparoscopy showed that up to 37.5% of patients (15/40) presented bowel involvement. Variables were clearly more evaluable with than without BP.

CONCLUSION

TVUS with BP has a higher accuracy than TVUS without BP. BP allows and facilitates the detection of more rectal nodules of DIE in patients with suspected endometriosis and surgical criteria.

摘要

研究目的

比较肠道准备(BP)前后经阴道超声(TVUS)检测和描述深部浸润性子宫内膜异位症(DIE)肠道结节的准确性,并与腹腔镜检查结果进行对比。

设计

配对数据的前瞻性研究(加拿大工作组分类II.1)。

地点

一所三级大学医院,时间为2014年11月至2015年11月。

患者

一组等待子宫内膜异位症手术的女性。

干预措施

通过两次经阴道超声对患者的直肠壁和乙状结肠下段进行评估:第一次超声检查前未进行肠道准备,第二次在进行3天低渣饮食,并在经阴道超声检查前12小时和3小时分别进行两次250毫升灌肠后进行。

测量指标和主要结果

将肠道准备前后经阴道超声显示的直肠乙状结肠结节的有无与腹腔镜检查结果进行比较。40例平均年龄为36.8±5.0岁的患者纳入研究。通过将组织学确诊的手术结果(肠道结节的有无及定位)与两次经阴道超声检查(肠道准备前后)的结果进行比较,其敏感性、特异性和Cohen kappa系数分别为100%、96%和0.95,以及73%、88%和0.61。腹腔镜检查显示,高达37.5%的患者(15/40)存在肠道受累。与未进行肠道准备相比,进行肠道准备时变量更易于评估。

结论

进行肠道准备的经阴道超声比未进行肠道准备的经阴道超声准确性更高。肠道准备有助于在疑似子宫内膜异位症且符合手术标准的患者中检测到更多深部浸润性子宫内膜异位症的直肠结节。

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