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角膜胶原交联术联合核黄素光化学角膜切削术治疗圆锥角膜。

Conductive keratoplasty followed by collagen cross-linking with riboflavin-UV-A in patients with keratoconus.

机构信息

From the Department of Ophthalmology, Vardinoyannion Eye Institute of Crete, University of Crete, Crete, Greece.

出版信息

Cornea. 2010 Feb;29(2):239-43. doi: 10.1097/ICO.0b013e3181a818ab.

Abstract

PURPOSE

To evaluate the combined effect of conductive keratoplasty (CK) followed by corneal collagen cross-linking (CXL) in 2 patients with keratoconus.

METHODS

CK spots were applied on the flatter side of the cornea followed by CXL using riboflavin and UV-A light.

RESULTS

Immediately after CK, a significant corneal topographic improvement was observed. The CK effect regressed 3 months postoperatively and remained unchanged until the sixth postoperative month in both patients.

CONCLUSION

Corneal remodeling with CK in patients with keratoconus seems to have a temporary effect despite the subsequent application of CXL.

摘要

目的

评估角膜胶原交联(CXL)联合传导性角膜成形术(CK)治疗圆锥角膜的效果。

方法

在角膜较平坦的部位施行 CK 治疗,随后应用核黄素和 UV-A 光施行 CXL。

结果

施行 CK 后即刻观察到显著的角膜地形学改善。在两名患者中,CK 作用在术后 3 个月消退,直到术后第 6 个月都没有变化。

结论

尽管施行 CXL,但 CK 治疗圆锥角膜后的角膜重塑似乎仅具有暂时效果。

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