Yokoyama K, Asano Y, Murakawa T, Takada M, Ando T, Sakai N, Yamada H, Iwata H
Department of Neurosurgery, Takayama Red Cross Hospital, Gifu, Japan.
J Neurosurg. 1991 Apr;74(4):585-9. doi: 10.3171/jns.1991.74.4.0585.
Brain arteriovenous malformations are considered to originate from a congenital maldevelopment of the brain vessels. Although there have been occasional reports suggesting a familial incidence of these lesions, data for only 10 families have been accumulated in the literature. The authors report on six such cases in three families. This high rate of occurrence of familial cases suggests an involvement of genetic factors.
脑动静脉畸形被认为源于脑血管的先天性发育异常。尽管偶尔有报告提示这些病变存在家族性发病情况，但文献中仅积累了10个家族的数据。作者报告了三个家族中的六例此类病例。家族性病例的这种高发生率提示存在遗传因素的参与。
