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儿童颅内与脊髓动静脉畸形并存:两例儿科病例报告及文献综述

Concurrent intracranial and spinal arteriovenous malformations: Report of two pediatric cases and literature review.

作者信息

Shallwani Hussain, Tahir Muhammad Z, Bari Muhammad E

机构信息

Student, Medical College, Aga Khan University Hospital, Karachi, Pakistan.

出版信息

Surg Neurol Int. 2012;3:51. doi: 10.4103/2152-7806.96074. Epub 2012 May 14.

Abstract

BACKGROUND

Concurrent intracranial and spinal arteriovenous malformations (AVMs) are very rare with only a few cases being reported in literature. Two of the rare concurrent intracranial and spinal AVM cases are presented.

CASE DESCRIPTION

Case 1 is a 12-year-old girl with headache and motor disturbances in the lower limbs. Her spinal and brain angiogram was done and she was diagnosed to have a spinal AVM at level T8-T9 and an intracranial AVM in the left mesial temporal lobe. Her spinal AVM was embolized, while no treatment was given for her intracranial AVM. Case 2 is a 10-year-old girl who presented with headache and quadriparesis. Her brain and spinal angiogram revealed an intracranial AVM in the left parietal lobe and a spinal AVM at level C2, respectively. Craniotomy and excision was done for her intracranial AVM and embolization for the spinal AVM.

CONCLUSION

It is proposed that multiple AVMs may be a result of yet unrevealed pathogenesis or strong embryogenetic anomaly, which may be different from that involved in single AVM. With lack of consensus over the best therapeutic strategy, multimodality treatment based on the individual's needs is suggested.

摘要

背景

颅内和脊髓动静脉畸形(AVM)同时存在的情况非常罕见,文献中仅报道了少数病例。本文介绍了两例罕见的颅内和脊髓AVM同时存在的病例。

病例描述

病例1是一名12岁女孩,有头痛和下肢运动障碍。她接受了脊髓和脑血管造影,被诊断为T8-T9水平的脊髓AVM和左侧颞叶内侧的颅内AVM。她的脊髓AVM接受了栓塞治疗,而颅内AVM未进行治疗。病例2是一名10岁女孩,表现为头痛和四肢瘫。她的脑和脊髓血管造影分别显示左侧顶叶有颅内AVM和C2水平有脊髓AVM。对她的颅内AVM进行了开颅手术切除,对脊髓AVM进行了栓塞治疗。

结论

有人提出,多发性AVM可能是尚未揭示的发病机制或强烈胚胎发育异常的结果,这可能与单一AVM的发病机制不同。由于对最佳治疗策略缺乏共识,建议根据个体需求进行多模式治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dfe6/3356988/fb0c0cfb0981/SNI-3-51-g001.jpg

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