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儿童肾移植前后的皮肤疣。

Cutaneous warts in children before and after renal transplantation.

机构信息

Children's Renal and Urology Unit, Queens Medical Centre Campus, Nottingham University Hospitals NHS Trust, Nottingham, UK.

出版信息

Pediatr Nephrol. 2010 May;25(5):941-6. doi: 10.1007/s00467-009-1390-8. Epub 2009 Dec 19.

Abstract

Cutaneous warts occur in 3.9-4.9% of children in the UK. The incidence is increased in organ transplant recipients and may be increased in patients with chronic kidney disease (CKD), since uraemia reduces the immune system's function. We surveyed the records from our CKD and renal transplant clinic to ensure patients with warts were identified and appropriately treated. Data were collected by questionnaire. The presence of warts, location, treatment, levels of pain and emotional upset were recorded. Nine of 49 (18.4%) pre-transplantation patients (33 male, median age 12.1 years) were currently suffering from warts compared with 17 of 60 (28.3%) post-transplantation patients (34 male, median age 13.9 years). A further 14 pre-transplantation and 16 post-transplantation patients had previously suffered from warts which had resolved. Forty-one patients had sought treatment for warts, mainly from primary care. Five patients, all having received transplants, were seen by a dermatologist. Self-rated levels of pain and emotional upset were generally low, apart from those of four adolescent patients who expressed significant emotional upset. We concluded that cutaneous warts are more common among CKD patients. Appropriate information and treatment are required before and after transplantation. The majority of warts can be treated in primary care, but selected patients with extensive warts that cause distress need early referral for dermatology opinion.

摘要

在英国,3.9%-4.9%的儿童患有皮肤疣。器官移植受者的发病率增加,慢性肾脏病(CKD)患者的发病率可能增加,因为尿毒症会降低免疫系统的功能。我们调查了我们的 CKD 和肾移植诊所的记录,以确保识别出患有疣的患者并对其进行适当治疗。数据通过问卷调查收集。记录疣的存在、位置、治疗、疼痛和情绪困扰程度。在 49 名移植前患者(33 名男性,中位年龄 12.1 岁)中有 9 名(18.4%)目前患有疣,而在 60 名移植后患者(34 名男性,中位年龄 13.9 岁)中有 17 名(28.3%)。另有 14 名移植前患者和 16 名移植后患者以前曾患过疣,现已痊愈。41 名患者因疣寻求治疗,主要来自初级保健。5 名患者(均接受过移植)由皮肤科医生就诊。自我评估的疼痛和情绪困扰程度通常较低,但有 4 名青少年患者表示情绪困扰显著。我们得出结论,皮肤疣在 CKD 患者中更为常见。在移植前后需要提供适当的信息和治疗。大多数疣可以在初级保健中治疗,但有少数患有广泛疣且感到困扰的患者需要早期转介皮肤科医生。

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