肾移植受者寻常疣中人类乳头瘤病毒的临床、组织病理学特征及分型

Clinical and histopathological characterization and typing of the human papillomavirus in common warts of kidney transplant recipients.

作者信息

Martelli-Marzagão Flavia, Yamashiro Alberto Shodi, Ogawa Marilia Marufuji, Santos Gildo Francisco dos, Tomimori Jane, Porro Adriana Maria

机构信息

Universidade Federal de São Paulo, SP, Brasil.

出版信息

An Bras Dermatol. 2010 Sep-Oct;85(5):743-6. doi: 10.1590/s0365-05962010000500027.

DOI:10.1590/s0365-05962010000500027

PMID:21152808

Abstract

The prevalence of skin lesions caused by the human papillomavirus (HPV) is high in kidney transplant patients. Twenty recipients of kidney transplants with a diagnosis of common warts were evaluated. HPV detection was performed by polymerase chain reaction (PCR) using the MY09/MY11 and RK91 primers. HPV typing was performed by restriction fragment length polymorphism analysis and direct sequencing. The presence of HPV was identified in 10 patients (50%) and the types identified were HPV-2, 27, 29, 34 and 57.

摘要

人乳头瘤病毒（HPV）引起的皮肤病变在肾移植患者中很常见。对20例诊断为寻常疣的肾移植受者进行了评估。使用MY09/MY11和RK91引物通过聚合酶链反应（PCR）进行HPV检测。通过限制性片段长度多态性分析和直接测序进行HPV分型。在10例患者（50%）中检测到HPV，鉴定出的类型为HPV-2、27、29、34和57。