Fortina Anna Belloni, Piaserico Stefano, Alaibac Mauro, Caforio Alida L P, Brandolisio Lara, Zacchello Graziella, Zanon Giovanni Franco, Zancan Lucia, Peserico Andrea
Department of Pediatrics, University of Padua, Via Giustiniani 3, 35128 Padua, Italy.
Transpl Int. 2005 Mar;18(3):360-5. doi: 10.1111/j.1432-2277.2004.00069.x.
Only few data are available on skin disorders in pediatric organ transplant recipients. In order to describe the whole range of dermatological diseases in a population of pediatric organ transplant recipients, we studied a group of 217 consecutive organ transplant recipients (168 kidney, 29 heart, 19 liver, one lung) aged <18 years at transplantation followed at a single center. A total of 193 patients showed at least one skin disorder; 149 had more than one skin disease. The most common skin infections were warts (24.4%), pityriasis versicolor (20.7%), folliculitis (12.9%), intertrigo (6.5%); the most common drug side effects were hypertrichosis (69.6%), steroid acne (39.6%), gingival hyperplasia (29%) and severe xerosis (20.7%). Two patients (0.9%) developed nonmelanoma skin cancer. Our study summarizes the main skin complications in patients transplanted in childhood and underlines the necessity of regular dermatologic surveillance of these patients.
关于小儿器官移植受者皮肤疾病的可用数据很少。为了描述小儿器官移植受者群体中皮肤病的全貌，我们研究了一组217例连续的器官移植受者（168例肾移植、29例心脏移植、19例肝移植、1例肺移植），这些患者在移植时年龄小于18岁，均在单一中心接受随访。共有193例患者出现至少一种皮肤疾病；149例患有不止一种皮肤病。最常见的皮肤感染是疣（24.4%）、花斑糠疹（20.7%）、毛囊炎（12.9%）、擦烂（6.5%）；最常见的药物副作用是多毛症（69.6%）、类固醇性痤疮（39.6%）、牙龈增生（29%）和严重皮肤干燥（20.7%）。两名患者（0.9%）发生了非黑素瘤皮肤癌。我们的研究总结了儿童期移植患者的主要皮肤并发症，并强调了对这些患者进行定期皮肤科监测的必要性。
