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On the mechanism of internalization of alpha-synuclein into microglia: roles of ganglioside GM1 and lipid raft.
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Gene delivery by dendrimers operates via a cholesterol dependent pathway.
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The role of ganglioside GM1 in cellular internalization mechanisms of poly(amidoamine) dendrimers.
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A Patching and Coding Lipid Raft-Localized Universal Imaging Platform.
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The role of caveolin-1 and syndecan-4 in the internalization of PEGylated PAMAM dendrimer polyplexes into myoblast and hepatic cells.
Eur J Pharm Biopharm. 2014 Nov;88(3):658-63. doi: 10.1016/j.ejpb.2014.07.010. Epub 2014 Jul 30.
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Polyplex-induced cytosolic nuclease activation leads to differential transgene expression.
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Polymeric nucleic acid vehicles exploit active interorganelle trafficking mechanisms.
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Best practices for purification and characterization of PAMAM dendrimer.
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Efficient in vitro siRNA delivery and intramuscular gene silencing using PEG-modified PAMAM dendrimers.
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Synthetic gene transfer vectors II: back to the future.
Acc Chem Res. 2012 Jul 17;45(7):980-4. doi: 10.1021/ar200213g. Epub 2012 Feb 6.
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The role of ganglioside GM1 in cellular internalization mechanisms of poly(amidoamine) dendrimers.
Bioconjug Chem. 2009 Aug 19;20(8):1503-13. doi: 10.1021/bc900029k. Epub 2009 Jul 7.
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Missing pieces in understanding the intracellular trafficking of polycation/DNA complexes.
J Control Release. 2009 Oct 15;139(2):88-93. doi: 10.1016/j.jconrel.2009.06.031. Epub 2009 Jul 4.
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Nonviral vectors for gene delivery.
Chem Rev. 2009 Feb;109(2):259-302. doi: 10.1021/cr800409e.
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Polymer-based gene delivery: a current review on the uptake and intracellular trafficking of polyplexes.
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The effect of surface functionality on cellular trafficking of dendrimers.
Biomaterials. 2008 Aug-Sep;29(24-25):3469-76. doi: 10.1016/j.biomaterials.2008.04.038. Epub 2008 May 22.
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Pharmacological inhibition of endocytic pathways: is it specific enough to be useful?
Methods Mol Biol. 2008;440:15-33. doi: 10.1007/978-1-59745-178-9_2.
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Endocytosis inhibitors prevent poly(amidoamine) dendrimer internalization and permeability across Caco-2 cells.
Mol Pharm. 2008 Mar-Apr;5(2):364-9. doi: 10.1021/mp700089s. Epub 2008 Jan 4.
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Water-soluble carbosilane dendrimers protect phosphorothioate oligonucleotides from binding to serum proteins.
Org Biomol Chem. 2007 Jun 21;5(12):1886-93. doi: 10.1039/b703989a. Epub 2007 May 14.
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Nanoparticle interaction with biological membranes: does nanotechnology present a Janus face?
Acc Chem Res. 2007 May;40(5):335-42. doi: 10.1021/ar600012y. Epub 2007 May 3.

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