Double-edged genetic swords and immunity: lesson from CCR5 and beyond.
作者信息
Ahuja Sunil K, He Weijing
出版信息
J Infect Dis. 2010 Jan 15;201(2):171-4. doi: 10.1086/649427.
Abstract
摘要
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Hetero-oligomerization of CCR2, CCR5, and CXCR4 and the protean effects of "selective" antagonists.CCR2、CCR5和CXCR4的异源寡聚化以及“选择性”拮抗剂的多种效应。
J Biol Chem. 2009 Nov 6;284(45):31270-9. doi: 10.1074/jbc.M109.054809. Epub 2009 Sep 15.
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The Duffy-null state is associated with a survival advantage in leukopenic HIV-infected persons of African ancestry.达菲阴性状态与非洲裔白细胞减少的HIV感染者的生存优势相关。
Blood. 2009 Sep 24;114(13):2783-92. doi: 10.1182/blood-2009-04-215186. Epub 2009 Jul 20.
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Racial differences in endotoxin-induced tissue factor-triggered coagulation.内毒素诱导的组织因子触发凝血的种族差异。
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Reduced neutrophil count in people of African descent is due to a regulatory variant in the Duffy antigen receptor for chemokines gene.非洲裔人群中性粒细胞计数减少是由于趋化因子基因的达菲抗原受体中的一个调控变异。
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