CEIP associé, Service de Pharmacologie, CHU Clermont-Ferrand, Clermont-Ferrand, France.
Therapie. 2009 Nov-Dec;64(6):365-70. doi: 10.2515/therapie/2009051. Epub 2009 Dec 23.
The aim of this meeting was to describe the news trends about abuse and addiction of anxiolytics and hypnotics. The part II of this meeting reviewed several aspects of the withdrawing benzodiazepines focusing in particular on clinical symptoms, biological patterns, and strategies for discontinuation. The discontinuation is usually beneficial due to the importance of adverse effects induced by long-term use of benzodiazepines. Several clinicals options have been described including gradual tapering of the current benzodiazepine, substitution with a long acting benzodiazepines or treating the symptoms of withdrawal. Psychological interventions range from a simple support through counselling to expert cognitive-behavioural therapy. However more controlled clinical trials are needed to promote adequate and optimal patient care in management of benzodiazepine withdrawing.
本次会议的目的是描述有关苯二氮䓬类药物滥用和成瘾的最新趋势。本次会议的第二部分回顾了苯二氮䓬类药物戒断的几个方面，特别关注临床症状、生物学模式和停药策略。由于长期使用苯二氮䓬类药物引起的不良反应很重要，因此停药通常是有益的。已经描述了几种临床选择，包括逐渐减少当前苯二氮䓬类药物的剂量、用长效苯二氮䓬类药物替代或治疗戒断症状。心理干预从简单的支持到咨询再到专家认知行为疗法不等。然而，需要更多的对照临床试验来促进在苯二氮䓬类药物戒断管理中为患者提供充分和最佳的护理。
