Institute for the Study of Children, Families and Social Issues, Birkbeck University of London, United Kingdom.
Biol Psychol. 2010 Mar;83(3):169-75. doi: 10.1016/j.biopsycho.2009.12.005. Epub 2009 Dec 22.
Animal models suggest that stress-induced hormonal changes in the mother during pregnancy lead to enduring changes in the fetus and empirical links between prenatal maternal stress and negative child development have been discerned repeatedly in human studies. But the role of heritable personality traits has received little attention in the latter work. The goal of the current study was to investigate the relationship between maternal personality, psychological measures of maternal distress and maternal salivary cortisol during pregnancy. Maternal reports of personality (16 PF) and stress-related psychological measures (depression, pregnancy-related anxiety, perceived stress, negative life events) as well as salivary cortisol samples of 66 healthy pregnant women were collected in early and late pregnancy. Maternal trait anxiety proved related to all stress-related psychological measures and high anxiety predicted low baseline cortisol awakening levels in early pregnancy. Maternal trait anxiety is related to both psychological and biological stress measures during pregnancy.
动物模型表明，母亲在怀孕期间因压力导致的荷尔蒙变化会导致胎儿持久的变化，并且在人类研究中已经反复发现产前母亲压力与儿童负面发展之间存在实证联系。但在后者的研究中，遗传人格特质的作用几乎没有受到关注。本研究的目的是调查母亲人格、怀孕期间母亲的心理压力测量和唾液皮质醇之间的关系。在孕早期和孕晚期，66 名健康孕妇报告了人格特质（16PF）和与压力相关的心理测量（抑郁、妊娠相关焦虑、感知压力、负面生活事件），以及唾液皮质醇样本。特质焦虑与所有与压力相关的心理测量都有关，高焦虑预示着孕早期基础皮质醇唤醒水平较低。母亲的特质焦虑与怀孕期间的心理和生物压力测量都有关。
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