Srivastava Sucheta, Nadelman Celina
Department of Pathology and Laboratory Medicine, LAC+USC Medical Center, Los Angeles, CA 90033-1084, USA.
Diagn Cytopathol. 2010 Jul;38(7):533-7. doi: 10.1002/dc.21267.
Fine-needle aspiration (FNA) is a cost effective and low morbidity procedure in the initial assessment of salivary gland tumors. However, cytological assessment of ipsilateral synchronous tumors (which make up less than 0.3% of all salivary gland neoplasms) may pose diagnostic challenges. Therefore, a wholesome approach, including FNA with clinical and radiological correlation, is of utmost importance. Here, we report a unique case of Warthin tumor encased by a separate high-grade mucoepidermoid carcinoma that was first diagnosed on FNA. Another striking feature seen was the presence of chronic sialadenitis in the surrounding nonneoplastic salivary gland. The presence of two different neoplasms in the background of chronic sialadenitis raises the question of a possible causal relationship. Traditionally, there has been diagnostic difficulty when dealing with synchronous tumors of the salivary gland and the background of chronic sialadenitis may further complicate the diagnosis. FNA is very helpful and can give important cues to the diagnosis.
细针穿刺抽吸活检(FNA)是唾液腺肿瘤初始评估中一种经济有效且发病率低的检查方法。然而,对同侧同步肿瘤(占所有唾液腺肿瘤的比例不到0.3%)进行细胞学评估可能会带来诊断挑战。因此,一种全面的方法,包括结合临床和影像学检查结果的FNA,至关重要。在此,我们报告一例独特病例,即沃辛瘤被一个独立的高级别黏液表皮样癌包裹,该病例最初通过FNA诊断。另一个显著特征是在周围非肿瘤性唾液腺中存在慢性涎腺炎。在慢性涎腺炎背景下出现两种不同肿瘤引发了关于可能因果关系的问题。传统上,处理唾液腺同步肿瘤时存在诊断困难,而慢性涎腺炎背景可能会使诊断进一步复杂化。FNA非常有用,可为诊断提供重要线索。