Eviagil'skaia R A, Korosteleva N L, Kotel'nikova A V
Biokhimiia. 1977 Oct;42(10):1888-95.
Mitochondria from AA-cells are a unique model with separately finctioning 1st and 3rd points of energy coupling and with completely blocked 2nd coupling point. In vivo the terminal segment of the respiratory chain does not operate, cytochromes c and a+a3 remain oxidized, and dominating terminal oxidase appears to be a component inhibiting by salicylhydroxamate and bound with the respiratory chain via cytochromes b or ubiquinone pool. The blocking of the 2nd coupling point is due to firm and, probably, quantitative binding of AA with cytochromes b, especially with b559, and also to a partial denaturation of the complex III.
来自AA细胞的线粒体是一个独特的模型，其能量偶联的第一和第三点分别起作用，而第二偶联点完全受阻。在体内，呼吸链的末端部分不运作，细胞色素c和a+a3保持氧化状态，主要的末端氧化酶似乎是一种受水杨羟肟酸抑制并通过细胞色素b或泛醌池与呼吸链结合的成分。第二偶联点的阻断是由于AA与细胞色素b，特别是与b559的牢固且可能是定量的结合，也是由于复合物III的部分变性。
