University of Rostock, Rostock, Germany.
Cancer Res. 2010 Jan 1;70(1):12-3. doi: 10.1158/0008-5472.CAN-09-2676. Epub 2009 Dec 22.
Systems biology takes an interdisciplinary approach to the systematic study of complex interactions in biological systems. This approach seeks to decipher the emergent behaviors of complex systems rather than focusing only on their constituent properties. As an increasing number of examples illustrate the value of systems biology approaches to understand the initiation, progression, and treatment of cancer, systems biologists from across Europe and the United States hope for changes in the way their field is currently perceived among cancer researchers. In a recent EU-US workshop, supported by the European Commission, the German Federal Ministry for Education and Research, and the National Cancer Institute of the NIH, the participants discussed the strengths, weaknesses, hurdles, and opportunities in cancer systems biology.
系统生物学采用跨学科的方法对生物系统中的复杂相互作用进行系统研究。这种方法旨在破译复杂系统的涌现行为，而不仅仅关注其组成性质。随着越来越多的例子说明了系统生物学方法在理解癌症的发生、进展和治疗方面的价值，来自欧洲和美国的系统生物学家希望改变癌症研究人员对该领域的看法。在最近一次由欧盟委员会、德国联邦教育与研究部和美国国立卫生研究院国家癌症研究所支持的欧-美研讨会上，与会者讨论了癌症系统生物学的优势、劣势、障碍和机遇。
