Davies Andrew J, Kalson Nicholas S, Stokes Suzy, Earl Mark D, Whitehead Adam G, Frost Hannah, Tyrell-Marsh Ian, Naylor Jon
Manchester Altitude Research Society, University of Manchester Medical School, Manchester, UK.
Wilderness Environ Med. 2009 Winter;20(4):311-7. doi: 10.1580/1080-6032-020.004.0311.
To determine the incidence of acute mountain sickness (AMS), the frequency of summiting success, and the factors that affect these in trekkers on Kilimanjaro, one of the world's most summitted high-altitude peaks.
The study group comprised 312 trekkers attempting Mt Kilimanjaro summit by the Marango Route. Trekkers ascended over 4 or 5 days along a fixed ascent profile, stopping at 3 huts on ascent (2700 m, 3700 m, and 4700 m) before attempting the summit. Researchers were stationed at each hut for 16 days. Each night we measured heart rate, respiratory rate, blood pressure, oxygen saturation, and Lake Louise Score. We recorded the highest altitude that trekkers reached on the mountain.
Of 181 complete sets of data, 111 (61%) trekkers reached the summit, and 139 (77%) developed AMS. Physiological results were not related to summit success. The incidence of AMS and summiting success were similar in those on the 4- or 5-day route. Trekkers on the 5-day route who used acetazolamide were less likely to develop AMS and more likely to summit than were those not taking acetazolamide (P = <.05); this difference was not present with trekkers on the 4-day route.
The risk of developing AMS is high on Mt Kilimanjaro. Although taking an extra day to acclimatize with the use of acetazolamide did provide some protection against AMS, ideally trekkers need a more gradual route profile for climbing this mountain.
确定急性高原病(AMS)的发病率、登顶成功率以及影响乞力马扎罗山徒步旅行者这些情况的因素,乞力马扎罗山是世界上攀登人数最多的高海拔山峰之一。
研究组由312名试图通过马兰戈路线攀登乞力马扎罗山的徒步旅行者组成。徒步旅行者沿着固定的上升路线在4或5天内攀登,在尝试登顶前在上升途中的3个小屋停留(2700米、3700米和4700米)。研究人员在每个小屋驻扎16天。每天晚上我们测量心率、呼吸频率、血压、血氧饱和度和路易斯湖评分。我们记录徒步旅行者在山上到达的最高海拔。
在181套完整的数据中,111名(61%)徒步旅行者登顶,139名(77%)患上急性高原病。生理结果与登顶成功无关。在4天或5天路线的徒步旅行者中,急性高原病的发病率和登顶成功率相似。与未服用乙酰唑胺的5天路线徒步旅行者相比,服用乙酰唑胺的5天路线徒步旅行者患急性高原病的可能性较小,登顶的可能性较大(P = <.05);4天路线的徒步旅行者中不存在这种差异。
乞力马扎罗山发生急性高原病的风险很高。虽然多花一天时间使用乙酰唑胺进行适应性训练确实能提供一些预防急性高原病的保护,但理想情况下,徒步旅行者需要一条更平缓的路线来攀登这座山。