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恶性乳腺病变中肿瘤新生血管形成的一个例外。

An exception to tumour neoangiogenesis in a malignant breast-lesion.

机构信息

Friedrich Schiller University Jena - Institute for Diagnostic and Interventional Radiology, FSU Jena, Germany.

出版信息

Breast J. 2010 Mar-Apr;16(2):197-8. doi: 10.1111/j.1524-4741.2009.00875.x. Epub 2009 Dec 16.

DOI:10.1111/j.1524-4741.2009.00875.x
PMID:20030653
Abstract

Magnetic resonance-mammography is regarded as the most sensitive diagnostic modality in the detection of breast cancer. It uses the tumour neoangiogenesis to depict lesions after intravenous contrast agent injection. It is said, that for tumours exceeding a diameter of three millimetres contrast agent enhancement is mandatory. In our case report we describe a rare tumour growth condition. We observed a large invasive carcinoma (18 millimetres diameter) without contrast enhancement in breast MRI due to an almost missing tumour neoangiogenesis. The cancer had a low cellularity and a strong desmoplastic reaction.

摘要

磁共振乳腺摄影被认为是检测乳腺癌最敏感的诊断方式。它利用肿瘤新生血管生成在静脉注射造影剂后描绘病灶。据称,对于直径超过三毫米的肿瘤,造影增强是必需的。在我们的病例报告中,我们描述了一种罕见的肿瘤生长情况。我们观察到一个大的侵袭性乳腺癌(直径 18 毫米),由于肿瘤新生血管生成几乎缺失,在乳腺 MRI 中没有造影增强。该癌症细胞密度低,纤维组织反应强烈。

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