Miami Children's Hospital, Division of Allergy and Immunology, 3100 Southwest 62 Avenue, Miami, FL 33155, USA.
Allergy Asthma Proc. 2009 Nov-Dec;30(6):584-8. doi: 10.2500/aap.2009.30.3289.
Antihistamines have been used in the treatment of rhinitis since ancient times. Antihistamines can be used via oral or topical route for the treatment of allergic rhinitis, as well as nonallergic forms of rhinitis. The topical formulation of medications is the preferred treatment route used for many diseases. This article will investigate the differences in the route of antihistamines in the treatment of allergic rhinitis. A review of the literature was performed to investigate the differences between the use of oral and topical antihistamines in the treatment of allergic rhinitis. Antihistamines inhibit the mediators of inflammation that worsen the symptoms of allergic rhinitis. Intranasal and oral antihistamines are important options in the therapy of allergic rhinitis, and topical use may result in unexpected benefits to patients with allergic rhinitis.
抗组胺药自古以来就被用于治疗鼻炎。抗组胺药可通过口服或局部途径用于治疗过敏性鼻炎，以及非过敏性鼻炎。药物的局部制剂是许多疾病的首选治疗途径。本文将研究抗组胺药在治疗过敏性鼻炎中的途径差异。通过文献回顾，研究了口服和局部应用抗组胺药治疗过敏性鼻炎的差异。抗组胺药抑制加重过敏性鼻炎症状的炎症介质。鼻内和口服抗组胺药是过敏性鼻炎治疗的重要选择，局部使用可能会给过敏性鼻炎患者带来意想不到的益处。
