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获得优质的玻璃化冷冻卵母细胞胚胎。

Excellent embryo quality obtained from vitrified oocytes.

机构信息

Colorado Center for Reproductive Medicine, Lone Tree, Colorado, USA.

出版信息

Reprod Biomed Online. 2009 Dec;19(6):820-3. doi: 10.1016/j.rbmo.2009.09.017.

Abstract

Oocyte vitrification has the potential to expand tremendously the reproductive options for women desiring fertility preservation. Indeed, the number of publications regarding the reliability and efficiency of oocyte vitrification has increased exponentially over the past decade. The application of the technique to standard reproductive technologies depends on not only oocyte survival, but also the developmental potential and clinical outcomes from the resultant embryos. The aim of this study, therefore, was to examine the embryo quality obtained from vitrified, warmed oocytes in a standard infertility population. The results demonstrate that high quality blastocyst development can be expected with subsequent excellent obstetric and perinatal outcomes. These data support oocyte vitrification as a promising technique for fertility preservation.

摘要

卵母细胞玻璃化冷冻具有极大扩展有生育保存需求的女性生殖选择的潜力。实际上,在过去十年中,关于卵母细胞玻璃化冷冻可靠性和效率的出版物数量呈指数级增长。该技术在标准生殖技术中的应用不仅取决于卵母细胞的存活率,还取决于由此产生的胚胎的发育潜力和临床结局。因此,本研究的目的是检查标准不孕人群中解冻的卵母细胞获得的胚胎质量。结果表明,可预期获得高质量的囊胚发育,从而获得极好的产科和围产期结局。这些数据支持卵母细胞玻璃化冷冻作为一种有前途的生育保存技术。

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