Department of Obstetrics, Gynecology, and Reproductive Sciences, San Francisco General Hospital, and Bixby Center for Global Reproductive Health, University of California, San Francisco, San Francisco, CA 94110, USA.
Am J Obstet Gynecol. 2010 May;202(5):420-8. doi: 10.1016/j.ajog.2009.10.863. Epub 2009 Dec 23.
Intrauterine progestins, progesterone receptor modulators, and antagonists have many important current and potential gynecologic applications. This article will describe the evidence for use of intrauterine progestin for common gynecologic conditions beyond its important role in contraception. We will review the evidence for use of intrauterine progestin delivery for menorrhagia, endometriosis management, adenomyosis treatment, uterine fibroids, endometrial hyperplasia, and its concurrent use in women on hormone replacement therapy or tamoxifen.
宫内孕激素、孕激素受体调节剂和拮抗剂在妇科领域有许多重要的当前和潜在的应用。本文将描述宫内孕激素在避孕以外的常见妇科疾病中的应用证据。我们将回顾宫内孕激素用于月经过多、子宫内膜异位症管理、子宫腺肌病治疗、子宫肌瘤、子宫内膜增生以及与激素替代治疗或他莫昔芬联合应用的证据。
