电描记高频活动与癫痫。

Electrographic high-frequency activity and epilepsy.

机构信息

Neuroscience, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, United Kingdom.

出版信息

Epilepsy Res. 2010 Mar;89(1):60-5. doi: 10.1016/j.eplepsyres.2009.11.008. Epub 2009 Dec 23.

DOI:10.1016/j.eplepsyres.2009.11.008

PMID:20031373

Abstract

High-frequency electrographic activity (HFA) has a frequency of 80-600Hz. It can be observed interictally in epileptic foci and also at the onset of epileptic seizures. There are several hypotheses about how HFA is generated, and it has been suggested that the underlying mechanisms may play an important role in epileptogenesis and ictogenesis. The high specificity of HFA for epileptic foci is now used during presurgical evaluation to help localize epileptic focus. In this article we review the current state of knowledge regarding this phenomenon and challenges for the future studies focusing on HFA.

摘要

高频脑电图活动（HFA）的频率为 80-600Hz。它可以在癫痫灶中观察到，也可以在癫痫发作开始时观察到。关于 HFA 是如何产生的有几种假设，有人认为潜在的机制可能在癫痫形成和发作形成中发挥重要作用。HFA 对癫痫灶的高度特异性现在用于术前评估，以帮助定位癫痫灶。本文综述了目前对这一现象的认识以及未来研究 HFA 时面临的挑战。