Centers for Disease Control and Prevention, Atlanta, GA 30341, USA.
Am J Mens Health. 2010 Dec;4(4):353-60. doi: 10.1177/1557988309356101. Epub 2009 Dec 22.
Testicular cancer is rare but primarily affects young men. To characterize the current incidence of testicular cancer in the United States, U.S. Cancer Statistics data from 1999 through 2004 were examined. Age-adjusted (2000 U.S. standard) incidence rates were calculated for seminoma and nonseminoma testicular germ cell tumors (TGCTs). Hispanic men had the largest increase in incidence rates for nonseminomas, followed by non-Hispanic White men (annual percentage change of 3.2% and 1.9%, respectively, p < .05). Nonseminomas peaked at a younger age for Hispanic, American Indian/Alaska Native (AIAN), and Asian/Pacific Islander (API) men. Whereas 9.6% of TGCTs were diagnosed at a distant stage in non-Hispanic White men, more Hispanic (16.1%), Black (13.8%), AIAN (16.8%), and API (14.9%) men with TGCTs were diagnosed with distant stage. Monitoring incidence rates for rare cancers by race/ethnicity has improved with national population-based cancer registry coverage. Disparities in diagnosis stage have implications for effective treatment of TGCTs.
睾丸癌较为罕见，但主要影响年轻男性。为了描述美国目前睾丸癌的发病率，研究人员分析了 1999 年至 2004 年的美国癌症统计数据。计算了精原细胞瘤和非精原细胞瘤生殖细胞肿瘤（TGCT）的年龄调整（2000 年美国标准）发病率。非精原细胞瘤发病率的增长幅度在西班牙裔男性中最大，其次是非西班牙裔白种人（分别为 3.2%和 1.9%，p<.05）。西班牙裔、美洲印第安人/阿拉斯加原住民（AIAN）和亚洲/太平洋岛民（API）男性中非精原细胞瘤的发病年龄更早。在非西班牙裔白种人中，9.6%的 TGCT 诊断为远处转移期，而更多的西班牙裔（16.1%）、黑人（13.8%）、AIAN（16.8%）和 API（14.9%）男性的 TGCT 诊断为远处转移期。随着全国性基于人群的癌症登记覆盖范围的扩大，对罕见癌症发病率的种族/民族监测得到了改善。诊断阶段的差异对 TGCT 的有效治疗有影响。
