Goldberg C J, Dowling F E
Department of Orthopaedics, Our Lady's Hospital for Sick Children, Crumlin, Dublin, Ireland.
Spine (Phila Pa 1976). 1991 Jan;16(1):84-7. doi: 10.1097/00007632-199101000-00015.
This report investigates dimensions of hand and foot preference in 159 girls with idiopathic scoliosis diagnosed after the age of 8 years, 1,522 girls with clinically straight spines, and 132 with minor truncal asymmetry. It was found that, although there was no significant difference in hand or foot preference for individual items between scoliotic groups and controls, there was a statistically significant tendency for children with any degree of asymmetry to show uniform lateralization in the sense of consistency of side preference. Another, smaller group showed a tendency for scoliosis to be associated with clearly visible facial asymmetry, which itself correlated with handedness. It was concluded that theories of scoliosis need to include the frequently ignored minor observations, such as the well-known fact of lateralization of the curve, if they are to describe the condition completely. Because the asymmetry of cerebral lateralization is known to be genetically determined and because it is thought to result in other skeletal asymmetries, such as skull and limb inequality, it seemed reasonable to investigate the primary cause of that gross asymmetry, idiopathic scoliosis.
本报告调查了159名8岁后被诊断为特发性脊柱侧弯的女孩、1522名临床脊柱挺直的女孩以及132名有轻微躯干不对称的女孩的手足偏好情况。研究发现，虽然脊柱侧弯组与对照组在各个项目的手足偏好上没有显著差异，但任何程度不对称的儿童在偏好侧一致性方面表现出统一的偏侧化倾向，这在统计学上具有显著意义。另一组规模较小的人群显示，脊柱侧弯倾向于与明显可见的面部不对称相关，而面部不对称本身又与用手习惯相关。研究得出结论，如果要全面描述脊柱侧弯这种情况，脊柱侧弯理论需要纳入那些经常被忽视的细微观察结果，比如侧弯偏侧化这一众所周知的事实。由于大脑偏侧化的不对称是由基因决定的，并且人们认为它会导致其他骨骼不对称，如颅骨和肢体不等长，因此研究这种明显不对称的主要原因——特发性脊柱侧弯似乎是合理的。
