Wyatt M P, Barrack R L, Mubarak S J, Whitecloud T S, Burke S W
J Bone Joint Surg Br. 1986 Nov;68(5):714-8. doi: 10.1302/0301-620X.68B5.3782230.
Recent clinical studies have suggested that a neurological lesion may be a cause of adolescent idiopathic scoliosis and animal experiments have implicated the posterior column pathway. We have tried to determine if differences in neurological response could be detected and measured clinically, and have compared the threshold of detection of vibratory sensation in 20 girls with adolescent idiopathic scoliosis with that in 20 clinically normal age-matched controls. A highly significant reduction of the threshold of detection of vibration was seen in the scoliotic group compared to the controls (p less than 0.001). Curve magnitude did not correlate with this threshold for either the upper (r = 0.172) or lower extremity (r = 0.126). Significant asymmetry between right- and left-sided thresholds to vibration was demonstrated in the scoliotic group. Our study supports the concept that an aberration in the function of the posterior column pathway of the cord may be of primary importance in the aetiology of idiopathic scoliosis. A clinically practical test to measure this function is presented.
近期的临床研究表明，神经病变可能是青少年特发性脊柱侧凸的一个病因，动物实验已表明后柱通路与此有关。我们试图确定是否能在临床上检测和测量神经反应的差异，并比较了20名青少年特发性脊柱侧凸女孩与20名年龄匹配的临床正常对照者的振动觉检测阈值。与对照组相比，脊柱侧凸组的振动检测阈值显著降低（p<0.001）。无论是上肢（r = 0.172）还是下肢（r = 0.126），曲线严重程度均与该阈值无关。脊柱侧凸组两侧振动阈值存在显著不对称。我们的研究支持这样一种观点，即脊髓后柱通路功能异常可能在特发性脊柱侧凸的病因中起主要作用。本文介绍了一种测量该功能的临床实用检测方法。
