Sironi S, Belloni C, Taccagni G L, DelMaschio A
Department of Radiology, University Hospital, Milan, Italy.
AJR Am J Roentgenol. 1991 Apr;156(4):753-6. doi: 10.2214/ajr.156.4.2003441.
In patients with cervical carcinoma, precise knowledge of parametrial tumor extension affects the therapeutic decision between surgery and radiation therapy. The purpose of this prospective study was to determine the efficacy of MR imaging in detecting the presence or absence of parametrial invasion in patients with cervical cancer thought clinically to be confined to the cervix. Twenty-five consecutive patients were included in the study. All patients underwent radical hysterectomy or total abdominal hysterectomy and had detailed histologic evaluation of the parametrium. Ten had pathologic evidence of parametrial invasion; in the remaining 15, no parametrial invasion was identified pathologically. MR findings were compared with pathologic findings in all cases. For determining parametrial involvement, MR imaging had an accuracy of 88%, a sensitivity of 100%, and a specificity of 80%. Our results suggest that MR imaging is a reliable means of assessing parametrial invasion by cervical cancer.
对于宫颈癌患者，准确了解宫旁组织肿瘤浸润情况会影响手术和放射治疗之间的治疗决策。这项前瞻性研究的目的是确定磁共振成像（MR成像）在检测临床认为局限于宫颈的宫颈癌患者是否存在宫旁浸润方面的有效性。该研究纳入了连续的25例患者。所有患者均接受了根治性子宫切除术或全腹子宫切除术，并对宫旁组织进行了详细的组织学评估。10例有宫旁浸润的病理证据；其余15例在病理上未发现宫旁浸润。所有病例均将MR成像结果与病理结果进行了比较。对于确定宫旁组织受累情况，MR成像的准确率为88%，敏感性为100%，特异性为80%。我们的结果表明，MR成像是评估宫颈癌宫旁浸润的可靠方法。
