Suppr超能文献

子宫颈癌和子宫内膜癌的分期

Staging of carcinoma of the uterine cervix and endometrium.

作者信息

Koyama Takashi, Tamai Ken, Togashi Kaori

机构信息

Department of Diagnostic Radiology, Graduate School of Medicine, Kyoto University, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.

出版信息

Eur Radiol. 2007 Aug;17(8):2009-19. doi: 10.1007/s00330-006-0555-0. Epub 2007 Jan 12.

Abstract

Carcinoma of the uterine cervix and endometrium are common gynecologic malignancies. Both carcinomas are staged and managed by means of the International Federation of Gynecology and Obstetrics (FIGO) staging system. In uterine cervical cancer, the FIGO staging system is determined preoperatively by limited conventional procedures. Although this system is effective for early stage disease, it has inherent inaccuracies in advanced stage diseases and does not address nodal involvement. CT and MR imaging are widely used as comprehensive imaging modalities to evaluate tumor size and extent, and nodal involvement. MR imaging is an excellent modality for depicting invasive cervical carcinoma and can provide objective measurement of tumor volume, and provides high negative predictive value for parametrial invasion and stage IVA disease. In contrast, endometrial cancer is surgically staged. Beside recognition of the important prognostic factors, including histologic subtype and grade, accurate assessment of the tumor extent on preoperative MR imaging is expected to greatly optimize surgical procedure and therapeutic strategy. Contrast-enhanced MR imaging can offer "one stop" examination for evaluating the depth of myometrial invasion cervical invasion and nodal metastases. Evaluation of myometrial invasion on MR imaging may be an alternative to gross inspection of the uterus during the surgery.

摘要

子宫颈癌和子宫内膜癌是常见的妇科恶性肿瘤。这两种癌症均采用国际妇产科联盟(FIGO)分期系统进行分期和管理。在子宫颈癌中,FIGO分期系统通过有限的传统检查在术前确定。尽管该系统对早期疾病有效,但在晚期疾病中存在固有的不准确性,且未涉及淋巴结受累情况。CT和MR成像被广泛用作综合成像方式,以评估肿瘤大小、范围及淋巴结受累情况。MR成像对于描绘浸润性宫颈癌是一种出色的方式,能够对肿瘤体积进行客观测量,并且对宫旁组织浸润和IVA期疾病具有较高的阴性预测价值。相比之下,子宫内膜癌采用手术分期。除了识别包括组织学亚型和分级在内的重要预后因素外,术前MR成像对肿瘤范围的准确评估有望极大地优化手术程序和治疗策略。对比增强MR成像可为评估肌层浸润深度、宫颈浸润及淋巴结转移提供“一站式”检查。MR成像对肌层浸润的评估可替代手术中对子宫的大体检查。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验