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聚乳酸植入物修复跟腱断裂:磁共振成像评估

Repair of Achilles tendon ruptures with a polylactic acid implant: assessment with MR imaging.

作者信息

Liem M D, Zegel H G, Balduini F C, Turner M L, Becker J M, Caballero-Saez A

机构信息

Department of Medical Imaging, Presbyterian Medical Center, Philadelphia, PA 19104.

出版信息

AJR Am J Roentgenol. 1991 Apr;156(4):769-73. doi: 10.2214/ajr.156.4.2003444.

DOI:10.2214/ajr.156.4.2003444
PMID:2003444
Abstract

An investigational tendon repair device composed of a polymer of lactic acid (PLA) is currently undergoing multicenter clinical trials for use in repairing rupture of the Achilles tendon. The advantages of the PLA device include high tensile strength and the induction of a rapid proliferative tissue response resulting in a shorter rehabilitation period than with conventional surgical repair. We reviewed 16 MR examinations performed in 10 patients 3-35 months after repair to characterize the MR appearance. All 16 T1-weighted sagittal images revealed a thickened fusiform tendon with streaks of moderate signal within the tendon corresponding to the PLA device and its surrounding collagenogenic response. The double-echo T2-weighted axial images at the mid tendon level demonstrated progressive changes in the signal pattern of the central portion of the tendon that reflected the maturation of the healing tendon. All tendons repaired with PLA implants were uniformly hypertrophied relative to the contralateral normal side because of the induced proliferative collagenogenic ingrowth. Two follow-up MR examinations were performed in six patients and showed mean reductions in tendon caliber of 24% and 30% at the mid and inferior levels. MR imaging of the Achilles tendon repaired with PLA implants shows a diffusely thickened tendon with streaks of signal within the tendon that distinguish it from tendons repaired by conventional techniques.

摘要

一种由乳酸聚合物(PLA)制成的实验性肌腱修复装置目前正在进行多中心临床试验,用于修复跟腱断裂。PLA装置的优点包括高拉伸强度以及诱导快速增殖的组织反应,从而使康复期比传统手术修复更短。我们回顾了10例患者在修复后3至35个月进行的16次磁共振检查,以描述磁共振表现。所有16幅T1加权矢状位图像均显示肌腱呈梭形增厚,肌腱内有条状中等信号,对应于PLA装置及其周围的胶原生成反应。肌腱中部水平的双回波T2加权轴位图像显示肌腱中央部分信号模式的渐进性变化,这反映了愈合肌腱的成熟过程。由于诱导的增殖性胶原向内生长,所有用PLA植入物修复的肌腱相对于对侧正常侧均均匀肥大。对6例患者进行了两次随访磁共振检查,结果显示肌腱中部和下部水平的直径平均分别减小了24%和30%。用PLA植入物修复的跟腱的磁共振成像显示肌腱弥漫性增厚,肌腱内有条状信号,这使其与用传统技术修复的肌腱有所区别。

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