Service de rhumatologie, CHU de Poitiers, rue de Milétrie, 86021 Poitiers, France.
Joint Bone Spine. 2010 Jan;77(1):47-9. doi: 10.1016/j.jbspin.2009.11.002.
To determine the prevalence and distribution of the various forms of juvenile idiopathic arthritis (JIA) in the Poitou-Charentes region of Western France.
We surveyed all the practicing rheumatologists and pediatricians in the study region for cases of JIA meeting ILAR criteria seen in 2006 among the population of 305,198 children younger than 16 years of age who resided in the study region. The survey was conducted by means of a questionnaire followed by a phone call. Cases of JIA identified by the survey were reviewed retrospectively.
We identified 48 children with JIA, which yielded a prevalence of 15.7/100,000. Mean age at diagnosis was 6.6 years (range, 1-15 years). Oligoarticular disease was the most common pattern, with 20 (41.6%) patients, a mean age of 4.9 years at diagnosis, and 80% of females. Oligoarticular disease was associated with the best outcomes, and only two (2/20, 10%) patients in this subgroup required disease-modifying therapy. Enthesitis-related arthritis contributed eight (16.6%) patients, with a mean age at diagnosis of 10.7 years and 75% of males. There were nine patients with polyarticular disease and seven with systemic disease; disease severity was greatest in these 16 patients, of whom only two were not taking disease-modifying drugs or glucocorticoids.
The prevalence of JIA in Poitou-Charentes was similar to the prevalences reported in other regions of France.
确定法国西部普瓦图-夏朗德地区各种幼年特发性关节炎（JIA）的流行情况和分布情况。
我们调查了研究区域内所有的执业风湿病专家和儿科医生，以确定在研究区域内居住的 305198 名 16 岁以下儿童中，2006 年符合 ILAR 标准的 JIA 病例。调查采用问卷调查和电话随访的方式进行。对通过调查确定的 JIA 病例进行回顾性审查。
我们共发现 48 例 JIA 患儿，发病率为 15.7/100,000。诊断时的平均年龄为 6.6 岁（范围为 1-15 岁）。寡关节炎是最常见的类型，有 20 例（41.6%）患者，诊断时的平均年龄为 4.9 岁，女性占 80%。寡关节炎的预后最好，该亚组中只有 2 例（2/20，10%）患者需要进行疾病修饰治疗。附着点相关关节炎占 8 例（16.6%），诊断时的平均年龄为 10.7 岁，男性占 75%。有 9 例多关节炎和 7 例全身型疾病患者；这 16 例患者病情最严重，其中只有 2 例未使用疾病修饰药物或糖皮质激素。
普瓦图-夏朗德地区 JIA 的患病率与法国其他地区的报告相似。
