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全黄斑转位治疗脉络膜新生血管的长期随访。

Long-term follow-up of full macular translocation for choroidal neovascularization.

机构信息

Department of Ophthalmology and Visual Sciences, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.

出版信息

Am J Ophthalmol. 2010 Mar;149(3):453-7.e1. doi: 10.1016/j.ajo.2009.09.014. Epub 2009 Dec 29.

DOI:10.1016/j.ajo.2009.09.014
PMID:20035923
Abstract

PURPOSE

To report the long-term (>5 years) results of full macular translocation in patients with choroidal neovascularization (CNV).

DESIGN

Retrospective, interventional case series.

METHODS

This study involved 32 eyes of 32 patients who had undergone full macular translocation for CNV. The median follow-up was 6.5 years (range, 5.2 to 7.7 years). We evaluated the best-corrected visual acuity, fundus examination results obtained before and 1 and 5 years after operation, and postoperative complications.

RESULTS

At the 1-year follow-up, foveal retinal pigment epithelium atrophy was observed in only 3 eyes (12%), and the mean logarithm of the minimal angle of resolution (logMAR) visual acuity (VA) at that time (1.39 +/- 0.67) was not significantly changed from that before surgery (logMAR, 1.31 +/- 0.66) in 25 eyes with age-related macular degeneration (AMD). However, at 5-year follow-up, foveal retinal pigment epithelium atrophy increased (18 eyes; 72%), and final mean logMAR VA (1.88 +/- 0.76) was significantly lower (P < .01). Five eyes with myopic CNV maintained their VA from before operation (mean logMAR, 0.88 +/- 0.35) until final follow-up (mean logMAR, 0.73 +/- 0.31). The final VA was significantly better in myopic CNV than in exudative age-related macular degeneration on multiple regression analysis (P = .019).

CONCLUSIONS

Long-term follow-up of full macular translocation showed that the final VA was poor in age-related macular degeneration, but relatively better in myopic CNV.

摘要

目的

报告脉络膜新生血管(CNV)患者全 macular 移位的长期(>5 年)结果。

设计

回顾性、干预性病例系列。

方法

本研究纳入了 32 名患者的 32 只眼,这些患者因 CNV 而行全 macular 移位。中位随访时间为 6.5 年(范围,5.2 至 7.7 年)。我们评估了最佳矫正视力、手术前后 1 年和 5 年的眼底检查结果以及术后并发症。

结果

在 1 年随访时,只有 3 只眼(12%)观察到黄斑视网膜色素上皮萎缩,25 只年龄相关性黄斑变性(AMD)眼的平均最小分辨角对数(logMAR)视力(VA)(1.39 +/- 0.67)与术前(logMAR,1.31 +/- 0.66)相比无明显变化。然而,在 5 年随访时,黄斑视网膜色素上皮萎缩增加(18 只眼;72%),最终平均 logMAR VA(1.88 +/- 0.76)明显降低(P <.01)。5 只近视性 CNV 的 VA 保持不变,从术前(平均 logMAR,0.88 +/- 0.35)到最终随访(平均 logMAR,0.73 +/- 0.31)。多变量回归分析显示,近视性 CNV 的最终 VA 明显优于渗出性年龄相关性黄斑变性(P =.019)。

结论

全 macular 移位的长期随访结果表明,年龄相关性黄斑变性的最终 VA 较差,但近视性 CNV 的相对较好。

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Visual function 5 years or more after macular translocation surgery for myopic choroidal neovascularisation and age-related macular degeneration.近视性脉络膜新生血管和年龄相关性黄斑变性行黄斑转位手术后 5 年或更长时间的视力功能。
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