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下颌骨的现代重建。

Contemporary reconstruction of the mandible.

机构信息

Department of Otolaryngology-Head and Neck Surgery, Beth Israel Medical Center, Albert Einstein College of Medicine, New York, NY, USA.

出版信息

Oral Oncol. 2010 Feb;46(2):71-6. doi: 10.1016/j.oraloncology.2009.11.006. Epub 2009 Dec 29.

Abstract

Reconstruction of the mandible has evolved significantly over the last 40years. Early attempts were often disfiguring and wrought with complications but with the introduction of free tissue transfer of well vascularized bone in the 1970's there was a significant improvement in outcomes. In recent years the harvest, inset, and microvascular anatomosis have been refined to the point that success rates are reported as high as 99% throughout the literature. Focus has now shifted to optimizing functional and aesthetic outcomes after mandible reconstruction. This paper will be a review defect classification, goals of reconstruction, the various donor sites, dental rehabilitation, new advances, and persistent problems. Reconstruction of segmental mandibular defects after ablative surgery is best accomplished using free tissue transfer to restore mandibular continuity and function. Reestablishing occlusion and optimizing tongue mobility are important to post-operative oral function. Persistent problems in oro-mandibular reconstruction relate to the effects of radiation treatment on the native tissue and include xerostomia, dysgeusia, osteoradionecrosis and trismus. These problems continue to plague the oral cancer patient despite the significant advances that allow a far more complete functional restoration than could be accomplished a mere two decades ago.

摘要

过去 40 年来,下颌骨的重建技术已经取得了显著的发展。早期的尝试往往会造成畸形和并发症,但随着 20 世纪 70 年代游离组织移植术的出现,血管丰富的骨骼的应用显著改善了治疗效果。近年来,游离组织的获取、植入和微血管吻合技术已经得到了极大的改进,文献报道的成功率高达 99%。目前,人们的关注点已经转移到优化下颌骨重建术后的功能和美学效果上。本文将对缺损分类、重建目标、各种供区、牙修复、新进展和遗留问题进行综述。游离组织移植术是修复切除术后节段性下颌骨缺损的最佳方法,可恢复下颌骨的连续性和功能。重建咬合关系和优化舌运动能力对于术后口腔功能至关重要。口腔颌面部重建中的遗留问题与放射治疗对自体组织的影响有关,包括口干、味觉障碍、放射性骨坏死和牙关紧闭。尽管游离组织移植术等显著进展使患者的功能恢复程度远高于仅仅二十年前,但这些问题仍然困扰着口腔癌患者。

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