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1例进展期胃癌经S-1化疗后达到组织学完全缓解

[A case of advanced gastric cancer with histological complete response after S-1 chemotherapy].

作者信息

Yahara Noboru, Hayashi Hiroto, Furuya Takumi, Saeki Toshihiro, Hayashi Hideto, Inoue Yuka, Yanai Hideo, Ishigaki Noriko

机构信息

Department of Surgery, Kanmon Medical Center.

出版信息

Gan To Kagaku Ryoho. 2009 Nov;36(12):2300-2.

PMID:20037402
Abstract

A 58-year-old man of unresectable gastric cancer was treated with S-1 (120 mg/body/day) after gastrojejunostomy. After 5 courses of orally administration of S-1 for 4 weeks and withdrawal for 2 weeks, partial response (PR) was obtained clinically and distal gastrectomy was performed. The histological diagnosis showed no residue of carcinoma with both HE and immunohistochemical staining. The patient has been in good health and no recurrence has occurred for about 4 years and 4 months after resection.

摘要

一名58岁不可切除胃癌男性患者在胃空肠吻合术后接受S-1治疗(120毫克/体/天)。在口服S-1 5个疗程,疗程为4周用药、2周停药后,临床获得部分缓解(PR),随后进行了远端胃切除术。组织学诊断显示,苏木精-伊红(HE)染色和免疫组化染色均未发现癌残留。患者身体状况良好,切除术后约4年4个月未复发。

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