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Good and bad memories following rituximab therapy.利妥昔单抗治疗后的美好与糟糕回忆。
Arthritis Rheum. 2010 Jan;62(1):1-5. doi: 10.1002/art.25039.
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Immunization responses in rheumatoid arthritis patients treated with rituximab: results from a controlled clinical trial.接受利妥昔单抗治疗的类风湿关节炎患者的免疫反应：一项对照临床试验的结果。
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B cell therapy for rheumatoid arthritis: the rituximab (anti-CD20) experience.类风湿关节炎的B细胞疗法：利妥昔单抗（抗CD20）的应用经验
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Rituximab therapy reduces activated B cells in both the peripheral blood and bone marrow of patients with rheumatoid arthritis: depletion of memory B cells correlates with clinical response.利妥昔单抗治疗可减少类风湿关节炎患者外周血和骨髓中的活化B细胞：记忆B细胞的耗竭与临床反应相关。
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When hematology meets ophthalmology: Cytomegalovirus retinitis in pediatric stem cell recipients.当血液学遇上眼科学：儿科干细胞接受者中的巨细胞病毒性视网膜炎
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Combination Treatment of Rituximab and Therapeutic Vaccines Affords Superior Tumor Suppression and Relapse Prevention for Non-Hodgkin Lymphoma.利妥昔单抗与治疗性疫苗联合治疗为非霍奇金淋巴瘤提供了卓越的肿瘤抑制和复发预防效果。
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Aberrant zonal recycling of germinal center B cells impairs appropriate selection in lupus.生发中心 B 细胞的异常区带循环会损害狼疮中的适当选择。
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Analysis of vaccine responses after anti-CD20 maintenance in B-cell lymphoma in the Balearic Islands. A single reference center experience.巴利阿里群岛抗 CD20 维持治疗后对 B 细胞淋巴瘤疫苗反应的分析。单参考中心经验。
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Cyclophosphamide induced early remission and was superior to rituximab in idiopathic membranous nephropathy patients with high anti-PLA2R antibody levels.环磷酰胺诱导早期缓解，在抗 PLA2R 抗体水平较高的特发性膜性肾病患者中优于利妥昔单抗。
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Persistent but atypical germinal center reaction among 3 SARS-CoV-2 vaccination after rituximab exposure.利妥昔单抗暴露后 3 次 SARS-CoV-2 疫苗接种后持续但非典型的生发中心反应。
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Hepatitis B Surface Antibody (Anti-HBs) Kinetics during Rituximab Chemotherapy and Performance of Hepatitis B Vaccine before Immunosuppression: Two Prospective Studies.利妥昔单抗化疗期间乙肝表面抗体（抗-HBs）动力学及免疫抑制前乙肝疫苗接种效果：两项前瞻性研究
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本文引用的文献

1
Immunization responses in rheumatoid arthritis patients treated with rituximab: results from a controlled clinical trial.接受利妥昔单抗治疗的类风湿关节炎患者的免疫反应：一项对照临床试验的结果。
Arthritis Rheum. 2010 Jan;62(1):64-74. doi: 10.1002/art.25034.
2
Humoral responses after influenza vaccination are severely reduced in patients with rheumatoid arthritis treated with rituximab.接受利妥昔单抗治疗的类风湿关节炎患者在流感疫苗接种后的体液免疫反应严重降低。
Arthritis Rheum. 2010 Jan;62(1):75-81. doi: 10.1002/art.25033.
3
Human marginal zone B cells.人边缘区B细胞。
Annu Rev Immunol. 2009;27:267-85. doi: 10.1146/annurev.immunol.021908.132607.
4
Human memory B lymphocyte subsets fulfill distinct roles in the anti-polysaccharide and anti-protein immune response.人类记忆B淋巴细胞亚群在抗多糖和抗蛋白质免疫反应中发挥着不同的作用。
J Immunol. 2008 Oct 15;181(8):5306-12. doi: 10.4049/jimmunol.181.8.5306.
5
T cell-independent development and induction of somatic hypermutation in human IgM+ IgD+ CD27+ B cells.人IgM+ IgD+ CD27+ B细胞中不依赖T细胞的发育及体细胞高频突变的诱导
J Exp Med. 2008 Sep 1;205(9):2033-42. doi: 10.1084/jem.20070447. Epub 2008 Aug 11.
6
Anti-CD20 therapy in patients with rheumatoid arthritis: predictors of response and B cell subset regeneration after repeated treatment.类风湿关节炎患者的抗CD20治疗：重复治疗后的反应预测因素及B细胞亚群再生
Arthritis Rheum. 2008 Jun;58(6):1566-75. doi: 10.1002/art.23473.
7
Maintenance of the plasma cell pool is independent of memory B cells.浆细胞库的维持独立于记忆B细胞。
Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4802-7. doi: 10.1073/pnas.0800555105. Epub 2008 Mar 13.
8
Rapid decline of influenza vaccine-induced antibody in the elderly: is it real, or is it relevant?老年人中流感疫苗诱导抗体的快速下降：这是真的吗，还是相关的？
J Infect Dis. 2008 Feb 15;197(4):490-502. doi: 10.1086/524146.
9
Maintenance of long-lived plasma cells and serological memory despite mature and memory B cell depletion during CD20 immunotherapy in mice.在小鼠CD20免疫治疗期间，尽管成熟B细胞和记忆B细胞耗竭，但长寿浆细胞和血清学记忆仍得以维持。
J Immunol. 2008 Jan 1;180(1):361-71. doi: 10.4049/jimmunol.180.1.361.
10
Therapeutic B cell depletion impairs adaptive and autoreactive CD4+ T cell activation in mice.治疗性B细胞耗竭会损害小鼠体内适应性和自身反应性CD4+T细胞的活化。
Proc Natl Acad Sci U S A. 2007 Dec 26;104(52):20878-83. doi: 10.1073/pnas.0709205105. Epub 2007 Dec 19.

Good and bad memories following rituximab therapy.

作者信息

St Clair E William

出版信息

Arthritis Rheum. 2010 Jan;62(1):1-5. doi: 10.1002/art.25039.

DOI:10.1002/art.25039
PMID:20039422
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2806494/
Abstract
摘要