Department of Hepato-bilio-pancreatic, Surgical Clinic, Clinical Center Nis, Nis 18000, Serbia.
World J Gastroenterol. 2010 Jan 7;16(1):119-22. doi: 10.3748/wjg.v16.i1.119.
Pancreatic schwannoma is a very uncommon tumor of the pancreas, with only 27 cases reported. Most pancreatic schwannomas are benign, with only four malignant tumors reported. We describe a case of giant malignant schwannoma of the pancreatic body and tail, which involved the transverse colon. The tumor was treated successfully with en bloc distal splenopancreatectomy and colon resection. This is believed to be the first reported radical operation for malignant schwannoma of the pancreatic body, with infiltration of the transverse colon, with excellent long-term results. The patient is alive and well 28 mo after the operation. The authors conclude that pancreatic schwannomas should be considered in the differential diagnosis of cystic neoplasms of the pancreas, although the diagnosis can only be confirmed by microscopic examination. In the case of the benign tumors, local excision is adequate, but in the case of malignant schwannoma, oncological standards must be fulfilled.
胰腺神经鞘瘤是一种非常罕见的胰腺肿瘤，仅有 27 例报道。大多数胰腺神经鞘瘤为良性，仅有 4 例恶性肿瘤报道。我们描述了 1 例胰体尾部巨大恶性神经鞘瘤的病例，该肿瘤累及横结肠。通过整块胰体尾切除和结肠切除术成功治疗了该肿瘤。这被认为是首例报道的浸润横结肠的胰体恶性神经鞘瘤的根治性手术，具有极好的长期结果。患者在手术后 28 个月时仍然存活且状况良好。作者得出结论，胰腺神经鞘瘤应在胰腺囊性肿瘤的鉴别诊断中加以考虑，尽管只有通过显微镜检查才能确诊。对于良性肿瘤，局部切除即可，但对于恶性神经鞘瘤，必须满足肿瘤学标准。
